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24 Cards in this Set

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In late pregnancy, which hormones and proteins increase in concentration or number in the myometrium?
-increase in estrogen secretion
-increase concentration of actin and myosin in uterus
-increase in gap junctions
-increase oxytocin and PGE receptors
What hormones in neonates stimulates lung maturation, increased liver glycogen levels, increase gluconeogenesis and increase in intestinal and digestive capacity?
Cortisol stimulates many changes to prepare fetus for life as neonate.
What is parturition?
The process of birthing the fetus.
What are the 4 phases of parturition?
-Phase 1 Quiescence
-Phase 2 Activation
-Phase 3 Stimulation
-phase 4 involution
Which parturition phase involves cervical softening and unresponsive or "paralyzed" uterine contractions?
Phase 1 Quiescence
Which partuition phase involves appearance of PGE2 and PGF2a and increased expression of oxytocin receptors. Also called "cervical ripening" because this phase is preparing the uterus.
Phase 2 Activation
Which phase of partuition involves uterine contraction, cervical dilation and placental expulsion (Process of labor)?
Phase 3 Stimulation
Which phase of parturition involves involution of uterus, re-epithelialization, BREAST FEEDING and return to regular size and weight?
Phase 4 Involution
Phase 3 of partuition is also known as the Labor stage. There are 3 Labor substages, briefly describe each.
1.) Cervical effacement and dilation (14 hours)
2.) fetal expulsion
3.) placental separation and expulsion
Which LABOR stage involves an increase in uterine contractions due to increased action of oxytocin and prostaglandins?
Stage 1
Which LABOR stage involves painful contractions, thinning of cervix, hypoxia and stretching of cervix and peritoneum?
Stage 1
Which LABOR stage involves rupture of the amniotic sac, VERY INTENSE contractions of uterus muscle and stressful compression of fetus?
stage 2
Stage occurs quickly
Which LABOR stage involves the expulsion of the umbilical cord and afterbirth?
Stage 3
What hormone induces lobuloalveolar growth of mammary gland during pregnancy/postpartum?
Prolactin
Prolactin along with what 2 other hormones work together to stimulate milk protein production?
Cortisol and insulin work with prolactin to stimulate transcription of the genes that encode milk proteins
Describe the way in which prolactin is secreted by the pituitary.
Prolactin is usually inhibited by dopamine from hypothalamus, however when you suck on the titty it will inhibit dopamine release, thus increase the secretion of prolactin.
Compare and contrast breast development during puberty regarding Estrogen and progesterone.
Estrogen stimulates creation of ducts and fat

Progesterone develops secretory lobules and alveoli
Does high estrogen during pregnancy inhibit or promote milk letdown/
It inhibits milk letdown. After birth, estrogen levels decrease and it allows milk to be released.
What are the components of breast milk?
Short chain FA
Sugar (lactose)
Proteins (casein)
Electrolytes
What does prolactin do specifically?
It stimulates a Janus kinase receptor to stimulate the production of milk lactose, casein and lipids.
T/F
The more milk you make, the more prolactin that will be produced?
True
increasing milk production will increase prolactin
What hormones is responsible for milk ejection?
How does it work?
Oxytocin

Causes contraction of alveolar myoepithelial cells
What hormones augments or promotes oxytocin action?

Which hormones block oxytocin action/
Estrogen promotes

Catecholamines block
Explain the effects of "sucking:".
Sucking inhibits GnRH release and suppresses LH and FSH release. May prevent ovulation and reduce fertility.