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58 Cards in this Set
- Front
- Back
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Normal BP
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< 120/80
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Pre HTN
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120-139 / or 80-89
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HTN Stage 1
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140-159 / or 90-99
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HTN Stage 2
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> 160 / or 100
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Hemolytic Anemia
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Premature destruction / removal
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Extravascular hemolysis
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Thru spleen
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B12
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Macrocytic anemia
Scissor walk Demyelination |
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Microcytic Anemia types
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Thalassemia
Iron Deficiency |
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Aplastic Anemia
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Something kills Precursor in BM
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Too much RBC
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Hematocrit > 42%
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Hemolytic Disease of Newborn
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Rhogam IgG binds to Rh antigens
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WBC normal count
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4-10k
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Leukocytosis
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High WBC count > 12k
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Leukopenia
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Not enough WBC count < 3k
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Acute Lymphoblastic Leukemia
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TdT+
Children T or B cell precursor |
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Acute Myelogenous Leukemia
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Adults
Aure Rods Liquid Phase Mouth ulcer |
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Chronic Lymphocytic Leukemia
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Adults - die with it
Blast Crisis - 2nd hit --> acute High WBC count - 150k B cell Solid |
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Chronic Myelocytic Leukemia
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Adults
Mature cell, low LAP (cell don't work) Blast crisis Ph' Chromosome Soft tissue met = choloroma |
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Ph Chromosome
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Chromic Myelocytic Leukemia
9:22 Tyrosine kinase ON |
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Petichae
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Low/non-working Platelet
Small ruptures ~rash |
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Thrombopoietin
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Increases platelets
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Thrombocytopenia
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Low platelets
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Hemophilia A
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Factor 8 enzyme (can't activate 10)
Made in liver Extrinsic Pathway |
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Hemophilia B
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Factor 9
Intrinsic X-mass |
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Von Willebrands
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Factor 8 glycoprotein
autosomal dominant Type 1 -reduced |
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Idiopathic Thrombocytopenia Perpera (ITP)
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Autoimmune destruction of platelets
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Lack TTP
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stabilizing factor
platelets stick to everything |
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Thromboplastin
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Tissue factor
activates clotting |
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Non-Hodgkin lymphoma
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Small Lymphocytic Lymphoma
no Germinal Centers, node is over run Liquid phase = Chronic Lymphocytic Leukemia Solid Phase = Lymphoma in lymph nodes Nodular pattern |
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Burkitt's Lymphoma
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American - Retroperitoneal
African - jaw, EB virus Starry sky’ appearance soilid |
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Hodgkin's Disease
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Autoimmune war
No tumor in node Reed-Sternberg: Bi nucleate cell, popcorn Bi modal distro Nodular Sclerosis Pattern |
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Stage 1
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SINGLE NODE/ site
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Stage 2
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2 or more on same side of Diaphragm
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Stage 3
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Both sides of diaphragm
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Stage 4
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Multiple disseminated foci
liver & BM |
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Multiple Myeloma
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Plasma cell malignancy
many groups in BM Bleeding - Protein coats platelets High IgG, Kappa chains |
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Arteriolosclerosis
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Sm vessels
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Atherosclerosis
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fatty plaques
large arteries Hyperhomocystinemia • Hollenhorst plaque |
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Atheromas
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Intimal lesions
large arteries fiberous cap - necrotic core |
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Arteriolosclerosis
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Areteriols
DM HTN |
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○ Saccular or berry
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Aneurysm
round, small congenital |
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Fusiform Aneurysm
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Really big
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Micro aneurysm
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Retina
congenital - neural DM, HTN |
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vasculitis
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Recurent Uveitis / Scleritis -> autoimmune
Syphilis PAN Giant Cell (Temporal) Arteritis |
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Polyarteritis nodosa (PAN)
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Vasculitis
sm - med arteries Hep B, autoimmune Skin ulcers hurts Kidneys --> HTN scleritis, uveitis |
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Giant Cell (Temporal) Arteritis
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Granulomatous
most common Vasculitis • Diagnosis by ↑ ESR, CRP and biopsy of TA |
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Wegener Granulomatosis
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• Necrotizing vasculitis, granulomas
Runny nose, sinuses inflammed Lungs, kidneys |
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Behçet Disease
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Vasculitis of small vessels
• HLA-B51 • Genital ulcers • Ocular inflammation (uveitis) (Often arthritis, NS symptoms |
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Reynaud Phenomenon
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Emotional, mensies
hyper sympathetic vasoconstriction migranes |
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• Primary Reynaud (also called Raynaud Disease)
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Idiopathic
• Smoking, caffeine worsen |
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• Secondary Reynaud (Reynaud Syndrome)
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Assoc with severe autoimmune / obstructive disorders, drugs,
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Thrombophlebitis
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Slow blood --> thrombus in vien
embolize --> lung --> dead |
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Vascular ectasia
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Dilation of vessel, not true tumor
Nevus flammeus Cork Wine stain Glaucoma associated w/Sterg Webber Syndrome (Tard) |
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Hemangiomas Cavernous
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Can get worse
associated with Von Hipple Lindow disease (retinal neoplasims) |
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Retinal Hemangioma
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Congenital
don't change |
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Kaposi Sarcoma
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Vascular neoplasm, proliferation endo
Slit like channels Mediterranean man AIDS Herpes |
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AngioSarcoma
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Malignant form of Kaposi
proliferation of endo • Often involve skin, breast, liver |
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Von Hippel-Lindau Disease
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Autosomal dominant
• Hemangioblastomas in cerebellum, spinal cord, kidney, retina • Mutation of VHL tumor suppressor |
