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Criteria for SBT
- corrected underlying cause
- SpO2 >88, FiO2 <0.5, PEEP< 8
- no MI
- hemodynamically stable
- no increased intracranial pressure
Exclusion criteria for SAT
- active seizures
- alcohol withdrawal
- escalating sedative dose
- NMB
- MI w/n 24 hr
- increased intracranial pressure
CI to succinylcholine use
- upper motor neuron injury
- multiple trauma
- burns
- hyperkalemia
High vagalytic agents
pancuronium
rocuronium
low vagalytic agent
vecuronium