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21 Cards in this Set

  • Front
  • Back
To contrast prescription drugs
the FDA must first prove that an herbal preparation is
Unsafe before it can order that a product be taken off the market.
In 2007 the FDA announced that dietary supplement manufacturers must now evaluate the
Composition
Identity
Purity
Strength

of their products and
Report all serious adverse events.
Most common uses:
mild to moderate depression and major depression
Adverse effects:
significant drug-herb interaction; induces cytochrome P450
St. John’s wort
Common uses are hyperlipidemia and atherosclerosis
Side effects are breath and body odor
GI upset
nausea
and flatulence.
Garlic
Has ability to improve blood flow in a variety of conditions
Ginkgo
A tonic to counteract weakness and fatigue
a restorative for declining stamina impaired concentration and as an aid to convalescence
May lower blood glucose and enhance sexual function.
Ginseng
Treats BPH and lower UTI symptoms
Very well tolerated with mild/rare GI symptoms.
Saw palmetto
Treats menopause related symptoms
Generally well tolerated with rare hepatitis.
Black cohosh
Are normally secreted by the adrenal cortex
and help in the synthesis of more than 40 different hormones.
DHEA Dehydroepiandrosterone and its metabolite
DHEAS
Reduced levels have been reported in pts with depression
cancer
T2DM
HIV
Alzheimer’s disease
Lupus
chronic kidney disease
anorexia
etc.
DHEA
It modestly increases testosterone levels in women
but not in men.
DHEA
It may increase the risk of estrogen- or androgen-dependent
malignancies
Pts
At high risk of prostate
ovarian
breast
or
uterine cancer

should be discouraged to use
DHEA
An amino sugar synthesized by chondrocytes and serves in the synthesis of cartilage
It is commercially prepared from crustacean shells.
Glucosamine
Normally present in the cartilage matrix and helps maintain articular fluid viscosity
inhibits enzymes that breakdown cartilage
and stimulate cartilage repair
It is extracted from cow trachea.
Chondroitin
Have been used in Europe to treat osteoarthritis
mostly of the knees
May take weeks or
months before symptoms are improved.
Glucosamine and Chondroitin
Well tolerated and safe with fewer side effects than nsaids
Efficacy of formulation remains questionable.
Glucosamine and Chondroitin
A fat-soluble provitamin that reside in the lipid layer of the mitochondria
Levels decrease with age
Deficits have been observed in pts
With chronic medical conditions
Well tolerated
Coenzyme Q10
The omega-3 fatty acids Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) is associated with many health benefits
especially against cardiovascular disease
What supplement?
Fish oil
GI upset
burping
fishy taste
loose stools
and nausea
Potential harm from mercury
dioxins
and polychlorinated biphenyls (pcbs)
Fish oil
A hormone synthesized by the pineal gland from the amino acid tryptophan
and it’s released in the circulation in response to environmental light-and-dark signals.
Melatonin
Considered safe at recommended doses of 5 mg or less for up to 2 years
Caution is advised in pts
Taking immunosuppressants or
those with vascular disorders or
infertility problems
Used to treat insomnia and jet lag
Melatonin