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88 Cards in this Set
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- Back
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25yo G2P1moderately obese delivering at 42 weeks, aprox 3700g. After 4 hrs of first stage of labor and 2 hrs second stage of labor, the fetal head delivers but is noted to be retracted back towards the patient's introitus. The fetal shoulders do not deliver, even with maternal pushing. NSM? Complication?
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Hyperflexion of maternal hips onto maternal abdomen and or suprapubic pressure. Complication: Maternal hemorrhage or Neontal shoulder dystocia bracial plexus injury.
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Risk factors for Shoulder Dystocia
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Macrosomia >4000g, Maternal obesity, prolonged 2nd stage, gestational DM.
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CASE 12: 45yo underwent total abdominal hysterectomy for symptomatic endometriosis 2 days earlier. She complains of rt flank tenderness. BP 130/90 HR 100bpm and temp 102'F. Heart and lungs are normal, abdomen is slightly tender diffusely with normal bowel sounds. Incision appears within normal limits. Exquisite right costovertebral angle tenderness is noted. NSD? most likely Dx?
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IVP or CT, right ureteral obstruction or injury. Cardinal ligament injury is common in hysterectomy.
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IVP shows possible obstruction, NSM?
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Cystoscopy to attempt retrograde stent passage
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55yo undergoes total abdominal hysterectomy and develops fever and flank tenderness.
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Ureteral Ligation
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33yo undergoes pelvic lymphectomy for cervical cancer. Rt ureter is meticulously and cleanly dissected free, and a penrose drain is placed around it to ensure its safety. She is asymptomatic until post op day 9, when she develops profuse nausea and vomiting and is noted to have ascites on ultrasound.
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Ureteral Ischemia leading to injury, overdissection of ureter may lead to devascularization injury. Urine in abdominal cavity is irritating leading to nausea and emesis.
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55yo who underwent vaginal hysterectomy for 3' vaginal prolapse 1 month ago, compains of constant leakage of fluid per vagina 7 days duration.
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Vesicovaginal Fistula
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44yo undergoes right salpingo-oophorectomy laparoscopically. Bipolar cautery is used to ligate the infundibular pelvic ligament. The next day she complains of fever and flank tenderness.
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Ureteral Thermal Injury, spread of thermal injury from cauderized tissue to surrounding structures.
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66yo menopause at 55, complains of 2 week history of vaginal bleeding. Next step? Dx?
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Perform a endometrial biopsy, endometrial cancer.
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Risk factor for endometrial cancer
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DM, HTN, Family, early menarche, late menopause, obesity, chronic anovulation, estrogen secretting tumor, unopposed estrogen
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Approach to postmenopausal bleeding
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Endometrial sampling (biopsy), catheter under suction to aspirate endometrial cells. If negative, Hysteroscopy for direct visualization. Or a Transvaginal US (>5mm endometrial stripe is abnormal)
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Most common cause of postmenopausal bleeding?
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Atrophic endometrium, friable tissue of the endometrium or vagina because of low estrogen levels. (Cancer can coexist with this, and must be ruled out)
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48yo postmenopausal undergoes pap smear which reveals atypical glandular cells. Best next step?
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Colposcopy, endocervical currettage, endometrial sampling
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57yo with HTN, DM, and PCOS complains of vaginal bleeding for 2 weeks. The endometrial sampling shows few fragments of atrophic endometrium. Estrogen replacement is begun. Patient continues bleeding 3 months later. Best next step?
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Hysteroscopic Examination
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Most important therapeutic measure in treatment of stage I endometrial cancer?
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Surgical Therapy
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30yo G5 P4 at 32 weeks gestation complains of significant bright red vaginal bleeding. 4 weeks ago she experianced some vaginal spotting after engaging in sexual intercourse. BP 110/60 HR 80bpm Temp 99'F Heart and lung examinations are normal. Abdomen is soft and uterus nontender. Fetal heart tones range from 140 to 150bpm. Next Step? Dx? Long term management?
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Ultrasound for placenta previa, with expectant management as long as the bleeding is not excessive. Cesarean delivery at 36 weeks gestation.
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Risk factor for placenta previa?
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Multipartity, Prior Cesarean, Prior Curettage, Previous Placenta Previa, Multiple Gestations
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Typical feature of placenta previa?
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Postcoital spotting, painless bleeding
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33yo at 37 weeks gestation, presents with moderately severe vaginal bleeding, sonogram shows placenta previa, best management for this patient?
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Cesarean Delivery
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22yo G1P0 at 34 weeks presents with moderate vaginal bleeding and no uterine contractions. Which of the following sequences of examination is most appropriate?
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Ultrasound examnination, Speculum examination, Digital examination
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18yo marginal placenta previa on US at 22 weeks gestation. Most appropriate management?
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Reassess placental position at 32 weeks.
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CASE 15: 22yo 35 weeks gestation, admits to cocaine abuse, complains of abdominal pain, and moderate vaginal bleeding. BP 150/90 HR 110bpm. Fundus reveals tenderness, and moderate amount of dark vaginal blood in vaginal vault. US shows no placental abnormalities. Cervix is 1cm dilated. Fetal heart tones range from 160 to 170bpm. Dx? Complications? Management?
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Dx Placental Abruption, Comp: Hemorrhage, fetal to maternal bleeding, coagulopathy, preterm delivery. Mgmt: Delivery (at 35 weeks, risk outweighs prematurity risk)
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Risk factors for Abruptio Placentae
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Short umbilical cord, Uteroplacental insufficiency, submucosal leiomyomata, uterine decompression (hydramnios), PROM, HTN, Smoking, Cocaine, Trauma
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US evaluation of Abruptio Placentae
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Poor, for assessment of abruption. Bc the freshly developed blood clot behind the placenta has the same sonographic texture as the placenta itself.
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Concealed abruption
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bleeding behind the placenta, no external bleeding noted.
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Fetomaternal hemorrhage
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fetal blood enters maternal circulation
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Courvelaire Uterus
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bleeding into the myometrium, discolored appearance to uterine surface.
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Clot found adherent to placenta
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Coagulopathy secondary to hypofigrinogenemia <150. NL:200-400
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Acid elution methodology
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Kleinhauer Betke Test, different solubilities of maternal vs fetal hemoglobin
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Maintain Hemoglobin above?
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>25% and urine output >30ml/hr
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In which condition would consumptive coagulopathy most likely be seen?
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Placental abruption
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In which of the following conditions is ultrasound an accurate and sensative method of diagnosis?
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Placenta previa, not abruption
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Which of the following is the most significant risk factor for abruptio placentae?
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Trauma
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Which of the following statements regarding placental abruption is the most correct?
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Couvelaire uterus arises from blood seeping into myometrium.
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CASE 16: 50yo G5P5 complains of 6mth history of postcoital spotting and malodorous vaginal discharge. She had a prior infection with syphilis and she is a smoker. Speculum examination reveals a 3 cm exophilic lesion on the anterior lip of the cervix. Next step? Dx?
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Biopsy of the lesion, Cervical Cancer
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Mean age of presentation for Cervical Cancer?
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51yo
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“case” plus flank tenderness or leg swelling?
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advanced cervical cancer.
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risk factors for cervical cancer
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early age of coitus, multiple sexual partners, history of STD's HIV HPV, early child bearing, low socioeconomics, cigarette smoking. Poor, smoking, sexually active.
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CIN
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cervical intraepithelial neoplasm, preinvasive lesion of cervix with abnormal cellular maturation, nuclear enlargement and atypia.
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clinical approach to postcoital spotting or abnormal pap smear.
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Cervical dysplasia or cancer should be suspected. Abnormal Pap smear is evaluated by colposcopy with biopsies. (5% acetic acid for acetowhite changes). Notice the change in color and vascular changes punctations vs atypical vessels-bad corkscrew and hairpin.
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cervical cancer is diagnosed, whats next?
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staging!! Tx: Early-surgery and radiation Late: radiotherapy (brachytherapy inplant radiation, teletherapy extermal beam)
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MCC of death due to cervical cancer?
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bilateral ureteral obstruction, uremia
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Most common subtypes of HPV associated with cancer?
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16,18,33, 45
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Gardasil vaccine covers?
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6, 11 (genital warts) and 16, 18
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Cervarix vaccine covers?
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16,18 only
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33yo Pap smear showing moderately severe cervical dysplasia (high grade Squamous intraepithelial neoplasia). Best next step?
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Colposcopic directed biopsy
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40yo Pap smear, which shows HSIL. Most accurate statement?
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If endocervixal curetting shows cervical dysplasia, then an excisional procedure is needed.
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When is HPV typing important?
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Only in atypical cells of undetermined significance.
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CASE 17: 24yo G2P2 delivered vaginally 8mths earlier. Delivery was complicated by postpartum hemorrhage requiring curettage of the uterus and blood transfusion of two units of erythrocytes. Complains of amenorrhea since her delivery. She is not able to breast feed her baby and denies taking any medication or having headaches or visual abnormalities. Pregnancy test is negative. Most likely Dx? Complications?
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Sheehan's syndrome, anterior pituitary necrosis. Possibly intrauterine adhesions from curretage. Complication: Anterior pituitary insufficiency, hypothyroidism, adrenalcortical insufficiency.
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postpartum hemorrage definition
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>500mL in vaginal delivery >1000mL in cesarean delivery
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Feature of intrauterine synchiae?
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Asherman syndrome, usually occurs after uterine curettage due to damaging of the decidua basalis (rendering endometrium unresponsive)
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Consistent with Sheehan's syndrome?
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Decreased prolactin levels, low TSH and hypotension in peripartum period.
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25yo presents with 6mths of amenorrhea. Pregnancy test is negative. What would be consistent with PCOS?
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estrogen excess, endometrial hyperplasia, glucose intolerance or DM, history of oligomenorrhea since menarche.
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22yo G3P2 at 40 weeks gestation complains of strong uterine contractions. She denies leakage of fluid per vagina. She denies medical illnesses. Antenatal history is unremarkable. Examination, her BP is 120/80 HR 85bpm. Cervix is 5cm dilated, vertex is at -3 station. Upon rupture of membranes, fetal hr drops to 70-80bpm for 4 min without recovery. Next step? Tx?
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Vaginal exam looking for umbilical cord prolapse, rope like structure in the cervical os. Once diagnosed place the px in trendelemburg position, keep pressure off the cord. Tx is elevation of presenting part digitally and emergent cesarean delivery.
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Predispose to umbilical cord prolapse?
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Unengaged presenting part or transverse fetal lie.
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Fetal Bradycardia?
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<110bpm for more than 10min
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Steps to take in fetal bradycardia?
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Confirm (US), vaginal exam, positional change, oxygen, IV fluid bolus, discontinue oxytocin.
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Causes of fetal bradycardia?
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1-Hyperstimulation with oxytocin, uterus will be tetanic, or frequent contractions (every minute). Tx relax uterus, terbutaline a B agonist. 2-Hypotension due to epidural, Tx IV hydration and ephedrine. 3- Umbilical cord prolapse 4 Uterine Rupture
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18yo woman who had undergone a previous low-transverse cesarean delivery is admitted for active labor. During labor, an intrauterine pressure catheter displays normal uterine contractions every 3 min with intensity up to 60 mmHg. Fetal bradycardia ensues. Dx
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Uterine rupture
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Maneuver improves oxygenation to the placenta?
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Lateral decubitus position. Supine position causes uterine compression on the vena cava, decreasing venous return of blood to heart, leading to supine hypotension.
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33yo G2P1 at 39 weeks gestation in active labor is noted to have a 1-min episode of bradycardia in the 100bpm range on external fetal heart rate tracing, which has not resolved. Her cervix is closed. Which is the best initial step in management of this patient?
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Asses maternal pulse, first step is to differentiate the fetal hr from maternal hr.
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30yo parous woman notes a watery breast discharge of 6mths duration. Her menses have been somewhat irregular. She denies a family history of breast cancer. The patient had been treated previously with radioactive iodine for Graves' disease. Currently, she is not taking any medications. On examination, she appears alert and in good health. Her blood pressure is 120/80 and HR 80bpm. The breast are symmetric and without masses. No skin retraction is noted. A white discharge can be expressed from both breast. No adenopathy is appreciated. The pregnancy test is negative. Dx? Next step? Mechanism for the disorder?
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Galactorrhea due to hypothyroidism, check serum prolactin levels and TSH levels. Hypothyroidism is associated with an elevated TRH level, which acts as a prolactin releasing hormone. The hyperporlacinemia then induces galactorrhea.
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Causes of hyperprolactinemia?
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Pituitary adenoma, pregnancy, breast stimulation, chest wall surgery/trauma and hypothyroidism. Drugs (tranquilizers, tricyclic antidepressants, antihypertensives, narcotics, oral contraceptive use) Hypothalamic causes (craniopharyngioma, sarcoidosis, histiocytosis, leukemia) Empty sella syndrome, Acromegaly, Renal Dz.
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Tx for low estrogen and hyperprolactinemia?
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Cabergoline, Bromocriptine (many SE)
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Microadenoma cure rate to surgery?
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Directly related to pretreatment prolactin levels, >200 poor prognosis. Pretreatment with bromocriptine may reduce the size.
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Which of the following clinical presentations is consistent with prolactin-secreting pituitary adenoma?
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central visual defect
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Hormones found in the posterior pituitary?
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ADH and Oxytocin
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33yo with microadenoma of pituitary gland becomes pregnant. She reaches 28 weeks gestation, she complains of headaches and visual disturbances. Which of the following is the best therapy?
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Oral bromocriptine therapy
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CASE 20: 24yo G1P0 at 28 weeks' gestation complains of a 2 week duration of generalized pruritus. She denies rashes, exposure to insects or allergies. Her medications include prenatal vitamines and iron suppliments. BP 100/60 HR 80bpm and weight 140lb. She is anicteric. The skin is without rashes. Fetal heart tones are in the 140bpm range. Dx?
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Cholestasis of pregnancy.
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Causes of puritus in pregnancy?
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Cholestasis of pregnancy, Pruritic urticarial papules and plaques of pregnancy, Herpes gestationalis
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Cholestasis of pregnancy?
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Pruritus with or without jaundice and no skin rash usually in 3rd trimester at night gradually increases with intesity. May recur in subsequent pregnancies and with the ingestion of OCP.
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Cholestasis of pregnancy puts the patient at risk for?
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Gallstones, prematurity, fetal distress and fetal loss especially when accompanied by jaundice
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Cholestasis of pregnancy tx?
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First line, antihistamines and cornstarch baths. Ursodeoxycholic acid and Cholestyramine may be also used.
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Pruritic urticarial papules and plaques of pregnancy?
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Intense itching and vesicles on abdomen and extremities, erythematous urticarial plaques and small papules surrounded by narrow, pale halos. Biopsy confirms shows superficial perivascular infiltrate of lymphocytes and histiocytes associated with edema of the papillary dermis. No adverse effects to fetus. Tx Topical steroids and antihistamines
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Herpes gestationalis?
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Not associated with herpes simplex virus. Intense pruritus and erythematous papules on the abdomen and extremities from IgG autoantibodies directed against the basment membrane. Increase incidence of fetal growth retardation and stillbirth Tx, oral corticosteroids
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Describe the pregnancy outcome of pruritic urticarial papules and plaques of pregnancy?
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No effect on the fetus
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33 yo G1P0 at 39 weeks gestation is in labor. She has been diagnosed with herpes gestationalis and has the characteristic pruritus and vesicular lesions on the abdomen. What does the patient need to be advised of in the neonate?
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Neonatal lesions may be noted and will resolve. Increased incidence of stillbirths and fetal growth retardation.
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23yo G0P0 complains of lower abdominal tenderness and subjective fever. She states that her last menstrual period started 5 days previous and was heavier than usual. She also complains of dyspareunia of recent onset. She denies vaginal discharge or prior sexually transmitted diseases. On examination, her BP 90/70, HR 90bpm and temperature 100.8'F. Heart and lung examination are normal. The cervix is somewhat hyperemic, and the uterus as well as adnexa are tender. Pregnancy test is negative. Dx? Long term complications?
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Pelvic Inflammatory Disease aka Salpingitis could lead to infertility or ectopic pregnancy.
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Inpatient criteria for PID?
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Fails outpatient management (follow up 48 hours), cannot tolerate or follow abx tx, pregnant, extremities of age >65, tubo ovarian abcess. Cannot rule out surgical emergency (appendicitis)
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Treatment for PID?
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depends on Inpatient vs Outpatient
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Inpatient Tx?
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cefotetan 2g IV 12hrs plus doxycycline 100mg DO 12 hrs (infusion rash) Clindamycin 900 IV 8 hrs, Gentamicin 2mg /kg 8 hrs. Ampicillin/Sulbactam 3g IV every 6hrs plus Doxycycline
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Outpatient Tx?
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Ceftriaxone 250mg IM with Doxyciline 100mg possible metronidazole 500mg
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Patient does not improve in 48 hrs next step?
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Consider US or laparoscopy to asses disease.
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Fitz Hugh Curtis syndrome
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perihepatic adhesions seen with salpingitis
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Tubo Ovarian Abscess
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Dx US tx Clindamycin or metronidazole
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18yo undergoes laparoscopy for an acute abdomen. Erythematous fallopian tubes are noted. Culture of the purulent drainage most likely would reveal?
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Multiple organisms, in acute salpingitis
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Most accurate method for diagnosing acute salpingitis?
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Laparoscopy is the gold standard
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33yo intrauterine contraceptive device develops symptoms of acute salpingitis. On laparoscopy, sulfer granules appear in the fimbria of the tubules. Most likely organism?
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Actinomyces species, gram positive anaerobe sensative to penicillin.
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