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116 Cards in this Set
- Front
- Back
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Trimesters
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12 and 28
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Timeline fetal development
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1wk
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implantation (trophoblasts b-hCG)
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3wk
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maternal fetal circulation
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12wks
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distinguish sex
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17wks
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fetal movements
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24wks
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surfactant production (earliest chance for survival)
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38wks
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full term
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Daily Caloric Intake during pregnancy
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~2500 kCal
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Calcium
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1200mg/day
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Folate
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1mg/day 4wks before attempted pregnancy
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Iron
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30mg/day
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Protien
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60g/day
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Weight Gain
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BMI <19 28-40lbs, 19-26 BMI 25-35lbs, >26 BMI 15-25 (normal should be 25 unless underweight (less) or over weight (more)
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Gain throughout pregnancy
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1st TM ~2lbs, 1lbs/week in 2nd and 3rd
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Physiology
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Caridovascular
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CO increases 40%, increased SV 10-30%, HR 12-18 BPM. Decrease in systolic/diastolic BP
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Respiratory
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Decrease in RV, FRC, ERV. Increased TV 40% and minute ventilation
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Renal
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GFR increases 40%
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Endocrine
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hPL-glucose intolerance, Increased Triglicerides, Cortisol
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Hematological
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RBC production, hematocrit decrease, hypercoaguable
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Screeing Initially
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EVERYTHING, CBC, Rh, Pap, Gono/Chlam, Urinanalysis, RPR, Rubella titers, PPD, Hep B, HIV, (Cystic Fibrosis in selected population)
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16-18wks
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Quadruple screen
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18-20
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US Dating, Abnormalities
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24-28
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1hr glucose challenge for DM
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23-36
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GBStrep screening and N. gono/Chlam selected population
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Transvaginal US vs Transabdominal
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b-hCG of 1500mIU/mL vs 6500mIU/mL
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Chorionic Villi Sampling
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9-12wks early detection
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Quadrple screen
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16-18wks a-feto, estradiol, hCG, Inhibin A
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21 trisomy
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Increased a-feto, estradiol. Decreased hCG, Inhibin
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18 trisomy
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all low, except Inhibin A
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NT
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a-feto high
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Percutaneous Umbilical Cord Sample
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10-22wks, late detection of genetic disroders or Rh sensativity
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Amniocentesis
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>16wks indicated after an abnormal quadruple screen, >35yo, risk of Rh sensativity
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Gestational DM Screening
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1hr 50g glucose tolerance test, >140 do 3hr 100g glucose tolerance test, fasting >105, 1hr-190, 2hr-165, 3hr-145.
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Gestational DM
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after 1st TM most frequent in 3rd, Screen at 24-28wks, abn glucose tolerance or a fasting glucose >105. Tx Diet/Exercise, Glyburide, Insulin. F/u fetal development stress test US
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Pregestational DM
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follow hemoglobin A1c, control glucose. 3rd trimester echocardiogram and US to follow fetal abnormalities
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Preeclampsia
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HTN, Proteinuria, Edema after 20wks gestation. BP >140/90 or 30mmhg rise in systolic or 15 in diastolic. Proteinuria 2+ or >4g/24 hrs. Tx definitive is delivery. severe or far from delivery: MgSO4 siezure prophylaxis, Hydralizine or Labetalol for HTN. (know history of epililepsy, not cured with delivery)
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HELP
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Hemolysis, Elevated Liver, Low Platelets. Form of preeclampsia with poor fetal prognosis.
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Eclampsia
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SIEZURES, tx MgSO4 or Diazapam for siezures, continue for 24hrs after delivery. 25% of siezures within 24hrs postpartum.
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Maternal Asthma
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Mild-Inhaled B-agonist, Mod Cromolyn or inhaled steriod, Severe oral corticosteriods.
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Epilepsy
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Phenobarbital, drug of choice in early pregnancy, low teratagenicity. Diazapam to break active siezures.
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Maternal Nause Vomiting
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usually in 1st TM. If severe, hyperemesis gravidum. Tx antacids, H2 antagonist or PPI.
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Maternal DVT
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US/Doppler studies. Tx IV heparin to treat active DVT PTT 2xNL. Low molecular wt heparin if significant time of delivery, switch to unfractionated 2wks till delivery. STOP all anticoagulants during labor and 6hrs to delivery. Anticoagulants continued postpartum (warfarin, caution when breast feeding)
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Drug Use
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Cocaine
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Maternal arrythmias, Fetal IUGR, premature, stroke
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Ethanol
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Fetal alcohol withdrawl symptoms (MR, IUGR, sensory and motor neuropathy, facial abnormalities (filthrum)).
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Hallucinogens
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Developmental Delays
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Marijuana
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Prematurity
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Opioids
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Maternal infections (needles). Fetal narcotic withdrawl, prematurity, IUGR,
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Stimulants
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Maternal malnutrition, arrhythmias. Fetal IUGR
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Tobacco
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Abrupto placenta, Placenta Previa. Spontaneous abortion, prematurity, IUGR, respiratory neonatal infections.
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Medications Teratogenic
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ACE-I
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Renal
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Aminoglycosides
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CN 8, skeletal abnormalities
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Carbamazepine
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Facial Abn, IUGR, MR, Cario, NTD
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Chemo
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Fetal demise
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Diazepam
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Cleft Palate
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DES
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Clear cells cancer of vagina
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Fluoroquilolones
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cartilage
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Heparin
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prematurity, fetal demise. safer than warfarin
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Iodide
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Goiter, hypothyroid, MR
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OCP's
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fetal demise, abnormal genitalia
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Phenobarbital
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neonatal withdrawl
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Phenytoin
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facial abnormalities, IUGR, MR, Cardio
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Retinoids
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CNS abnormalities, Cardiovascular abnormalites, facial and spontaneious abortion
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Sulfonamides
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Kernicterus
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Tetracycline
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skeletal, limb and teeth discoloration
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Thalidomide
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limb abnormalities
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Valproic Acid
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NTD, facial, cariovasacular, skeletal
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Warfarin
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Spontanoues abortion, IUGR, CNS, facial and MR
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Ectopic Pregnancy
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outside of uterus at ampula of fallopian tube, abdominal pain. b-hCG low for gestational age. Tx <6wks methotrexate, anything else IV hidration surgical excision.
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Spontaneous Abortion
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<20wks gestation, 25% all pregnancies. B-hCG assess fetal age, US to asses fetal viability.
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Threatend SA
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cervical os closed, no expelled uterine contents, US detects viable fetus Tx: bed rest, limited activity
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Inevitable SA
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cervical os opened, no expelled uterine contents, US may detect fetusTx: D&C
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Incomplete SA
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cervical os opened, some expelled uterine contents, Tx: D&C
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Complete SA
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cervical os closed, All expelled uterine contents, Tx: None
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Missed SA
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cervical os closed, no expelled uterine contents, US detects unviable fetus Tx: None
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Intrauterine Fetal Demise
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>20 weeks of gestation. Tx Dilation and Evacution if <24wks, induced labor if >28wks
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IUGR
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initial finding abd circumfrence <10th percentile
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Symmetric
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(baby issues or drugs) congenital infection, chromosomal abnormalities or maternal drug use Length:abdominal ratio normal
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Asymmetric
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(maternal or multiple) multiple gestations, poor maternal health, placental insufficiency. Length:abdominal ratio increased
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Fetal Lung Maturity
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L:S >2 or phosphatidylglycerol in amniotic fluid.
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Tocolytic Therapy
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MgSO4, terbutaline, ritodrine, indomethacin, nifedipine
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Premature Rupture of Membranes
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manual exam not performed due to increased infection risk, ferning, nitrazine paper blue. US confirm oligohydramnios and asses residual volume. Tx >34wks delivery. Chorioamnionitis delay deliver until anbiotics started.
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Preterm Labor
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before 38 wks, labor (>8uterine contractions/hr, cervical dilation and effacement).
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Placenta Previa
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Implantation near cervical OS, painless vaginal bleeding in 3rd trimester. US to determine location. Tx Tocolysis and Cesarean.
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Abruptio Placenta
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premature separation, painful vaginal bleeding, US inconsistently shows separation. Tx mild-bedrest, delivery or cesarean for hymodynamically unstable.
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Multiple Gestations
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Tx starting at 20wks weekly follow-up, 36wks activity restriction and frequetn nonstress tests. Vertex-vertex vaginal delivery, all other require caesarean.
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Non Stress Test
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Effects of fetal movement on heart rate. Normal reactive if 2 or more 15bpm accelerations fo fetal heart rate lasting 15 seconds each within 20 min
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Biophysical profile
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Nonstress test, Bishop Score: amiotic fluid index, fetal breathing rate, fetal movement, fetal tone 8-10 is good, anything else fetal distress
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amniotic fluid index
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5-23 cm
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fetal breathing
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>1 episode or rhythmic breathin lasting 20 sec in 30 min period
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fetal movements
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>2 episodes discrete fetal movement withing 30 min period
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fetal tone
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1> spine and limb extension with return to flexion
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Contraction Stress test
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beat to beat variability ~5 bpm, long-term heart rate variability, heart rate accelerations (2 accelerations of 15 bpm lasting at least 15 seconds within 20 minute period)
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Early
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head compression
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Late
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uteroplacental insufficiency, fetal hypoxia, prompt delivery
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Variable
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umbilical cord compression, change mother position
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Stages of Labor
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1- Latent
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start of uterine contractions till 4cm dilated. Time for 1' stage Nullparous 6-18 hrs Multiparious <10hrs
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Active
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4cm -10 cm
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2-Full
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10cm-Delivery, Null <3hrs Multi<30min
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3-Placenta
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<30min
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4-1st hr postpartum
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hemodynamic stabilization of mother for 1hr
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Fetal presentation
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fetal head down, chin tucked, occiput directed towards birth canal.
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Colostrum
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protiens, fat, minerals, IgA
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Breast Milk
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protiens, fat, water, lactose
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APGAR
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heart rate
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0-none 1-<100 2->100bpm
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respirations
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0-none 1-poor weak cry 2- good strong cry
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muscle tone
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0-poor 1-some movement 2- active movement
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stimulation
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0-none 1- grimace 2-strong cry
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color
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0-blue pale 1- pink torso 3-pink
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Hydatiform mole
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complete xx-father, incomplete fetal parts xxy, grape like vesicles US snowstorm appearance,
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Choriocarcinoma
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malignant trophoblastic neoplasm, CT metastasis
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