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23 Cards in this Set

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Zidovudine (AZT, ZDV)
Retrovir

A nucleoside reverse transcriptase inhibitor (NRTI)
Lamivudine (3TC)
Epivir

A nucleoside reverse transcriptase inhibitor (NRTI)
Emtricitabine (FTC)
Emtriva

A nucleoside reverse transcriptase inhibitor (NRTI)
Stavudine (d4T)
Zerit

A nucleoside reverse transcriptase inhibitor (NRTI)
Didanosine (ddl)
Videx EC

A nucleoside reverse transcriptase inhibitor (NRTI)
Abacavir (ABC)
Ziagen

A nucleoside reverse transcriptase inhibitor (NRTI)
Tenofovir (TDF)
Viread

A nucleoside reverse transcriptase inhibitor (NRTI)
AZT + 3TC

Zidovudine + Lamivudine
Combivir

BID


A nucleoside reverse transcriptase inhibitor (NRTI)
AZT + 3TC + ABC

Zidovudine + Lamivudine + Abacavir
Trizivir

BID

A nucleoside reverse transcriptase inhibitor (NRTI)
3TC + ABC

Lamivudine + Abacavir
Epzicom

A nucleoside reverse transcriptase inhibitor (NRTI)
FTC + TDF

Emtricitabine + Tenofovir
Truvada

A nucleoside reverse transcriptase inhibitor (NRTI)
Which nucleoside reverse transcriptase inhibitor (NRTI) causes renal dysfunction?
Tenofovir = Viread

Truvada has tenofovir in it.
Which nucleoside reverse transcriptase inhibitor (NRTI) doesn't have to be adjusted for renal dysfunction?
Ziagen

Abacavir (ABC)
Which nucleoside reverse transcriptase inhibitor (NRTI) requires a HLA B5701 test to determine the liklihood of a hypersensitivity reaction?
Abacavir (ABC)

Ziagen
Which 3 drugs have a high liklihood of causing lactic acidosis, pancreatitis, and lipoatrophy?
Stavudine, Didanosine, and Zidovudine

Combo products: Combivir and Trizivir
What can't be taken with d4T?
AZT (Zidovudine) and Didanosine (Videx EC)

Competes for the same site of action
What can't be taken with 3TC?
Emtricitabine (FTC)

Both are cytosine analogues
Which NRTI causes hyperpigmentation of palms?
Emtricitabine (FTC)

Truvada
Which NRTI can't be taken with AZT?
Stavudine (d4T)

Both are thymidine analogues
Which NRTI already has a phosphate on it?
Tenofovir (TDF)

Viread
Is the use of ddl tabs recommended?
NO!
Which NRTI causes Headache and BMS (neutropenia or anemia) in 30% of patients?
Zidovudine (AZT)

Retrovir and Trizivir
MoA for the nucleoside reverse transcriptase inhibitors?
Prematurely terminates DNA elongation by competing with endogenous deoxynucleotides for reverse transcriptase enzyme.