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32 Cards in this Set

  • Front
  • Back
Gram stain of E. coli
gram negative
Four classes of cell wall inhibitors
penicillins
cephalosporins
carbapenems
vancomycin
Three classes of protein synthesis inhibitors
macrolides
clindamycin
aminoglycosides
Two DNA inhibitors
fluoroquinolines
Metronidazole
Penicillin uses
Gram + cocci
Anaerobes
What are two beta-lactamase resistant penicillins
nafcillin
oxacillin
3 extended spectrum penicillins with an beta-lactamase
unasyn
augment
zosyn
As cephalosporin generations increase so does this
gram negative activity
1st generation cephalosporin
cefazolin
Clinical uses of cefazolin
UTIs
Surgical prophylaxis
2nd generations cephalosporins
cefuroxime
cefoxitin
cefotetan
What are the 4 third generation cephalosporins
ceftriaxone
ceftazidime
cefotaxime
cefixime
What are two additional clinical advantages of 3rd generation cephalosporins
more gram neg activity
cross BBB
What is the fourth generation cephalosporin
cefepime
What bacteria is cefepime used for
pseudomonas
Drug of choice for enterobacter
carbapenems
Carbapenem that can cause seizures
imipenem
When is vancomycin given orally
c diff
What is vanc active against
gram positive
What are the macrolilde drugs
azythromycin
erythromycin
clarithromycin
What organisms are macrolides effective against
gram + and -
Atypicals
mycobacteria
Drug of choice for chlamydia
macrolides
Drug of choice as penicillin substitutes
macrolides
What is clindamycin used for
anaerobes + and -
How are macrolides and clindamycin eliminated
liver
How are the cell wall inhibitors eliminated
renal
What kind of organisms are aminoglycosides used for
gram -
How do you treat NMB SE of aminoglycosides
neostigmine
Calcium gluconate
Block bacterial DNA synthesis by inhibiting bacterial topoisomerase 2
Fluoroquinilones
AB that can cause QT prolongation
fluoroquinilones
How is metronidazole metabolized
liver
What is metronidazole used for
intra-abd infections
protozoal infections