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66 Cards in this Set
- Front
- Back
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How to describe a path pot?
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What organ?
Where? What pathological process? Aetiologic clues Sequelae & complications Incidental and related DDx |
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How do you describe a lump?
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1) Size
2) Site 3) Shape 4) Surface 5) Margins 6) Tenderness 7) Consistency 8) Composition: consistency, fluid thrill, transillumination, resonance, pulsatility 9) Mobility/fixation 10) Overlying skin 11) Regional lymph nodes 12) Other |
What is the lesion?
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Left: Pedunculated polyp
Right: Sessile polyp |
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What are the types of large bowel polyps?
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Shape:
1) Sessile 2) Pedunculated Aetiology 3) Neoplastic - adenomatous polyp (>100 = FAP, Gardner's syndrome) 4) Hyperplastic - delayed shedding 5) Inflammatory - IBD (UC, CD) 6) Hamartomatous - Peutz-Jegher's syndrome Adenomatous polyps 7) Tubular (pedunculated) 8) Villous (sessile, malignant) Risk of malignancy (adenoma to adenocarcinoma): Polyp size (>2cm=50%) Architecture: Villous 40%, tubulovillous 20%, tubular 5% Severity of epithelial dysplasia |
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What are the risk factors for CRC?
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FAP, HNPCC, Adenomatous polyps
FHX IBD (esp. UC) Diet, smoking, EtOH DM, acromegaly Low dietary fiber intake Obesity, physical inactivity Irradiation |
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What is the adenoma-carcinoma sequence?
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Normal colonic epithelium Hyperproliferative Early Adenoma Late adenoma Carcinoma
- Ca develops from progressive accumulation of multiple genetic mutations - Most cancers: Chromosomal instability pathway A - HNPCC: Microsatellite instability pathyway B |
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What is the treatment for CRC?
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Surgical resection:
5 cm margins. Lymphovascular clearance (pericolic LNs) Mesentary Liver mets resected w/ 1-2cm margin + XRT/Chemo XRT+Chemo only in rectal ca. |
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What is the treatment for a Ca at the hepatic flexure?
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Right hemicolectomy
Caecum Ascending colon Part of transverse colon Omentum SMA branches: ileocolic, R colic, R branch of middle colic vessels Anastamosis of lieum to transverse colon. |
What is this lesion?
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IBD.CD radiological features
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4 S's
Stricture at the perianal ring String sign = luminal narrowing @ distal ileum Skip lesions = separation from surrounding loops Sinus tract = communication between pathologic space and cavity |
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IBD.UC radiological features
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"Lead pipe" colon = Loss of haustral markings
Shortening of colon Toxic megacolon: dilated lumen (>6cm) |
What is the lesion?
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|
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What are the perianal features of CD?
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50% of CD patients
Skin tags Fissures Perianal sepsis Anorectal strictures |
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CD vs UC:
Locations involved |
CD: Any part of GI tract (mouth to anus)
UC: Colon only, rectum always involved |
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CD vs UC:
Rectal bleeding |
CD: Uncommon
UC: Very common (90%) |
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CD vs UC:
Diarrhoea |
CD: Less prevalent
UC: Freuqent small stools |
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CD vs UC:
Abdo pain |
CD: Post-prandial / colicky
UC: Predefecatory urgency |
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CD vs UC:
Fever |
CD: Common
UC: Uncommon |
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CD vs UC:
Palpable mass |
CD: Frequent, RLQ
UC: Rare |
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CD vs UC:
Recurrence after surgery |
CD: Common
UC: Rare |
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CD vs UC:
Histologic features |
CD: Transmural distribution, focal inflammation, non-caseating granulomas, glands intact
UC: Mucosal distribution, diffuse inflammation, granulomas absent, gland destruction, crypt abscess |
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CD vs UC:
Endoscopic features |
CD: Apthoid ulcerations, patchy lesions
UC: Diffuse erythemia, friability, loss of normal vascular pattern, continuous lesions |
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CD vs UC:
Radiologic features |
CD: Strictures, fistula (=sinus tract), cobblestone mucosa, string sign (luminal narrowing), skip lesions
UC: Haustration loss, lead pipe appearance, shortening of colon, toxic megacolon (>6cm, dilated lumen) |
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CD vs UC:
Creeping mesenteric fat |
UC: Not seen
CD: Common |
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CD vs UC:
Serosa |
UC: Normal
CD: Granular, fibrosed or 'flared' |
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CD vs UC:
Depth of inflammation |
UC: Mucosal (rarely submucosal)
CD: Transmural (full thickness) |
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CD vs UC:
Wall thickening |
UC: Minimal, no fibrosis
CD: Common |
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CD vs UC:
Granulomas |
UC: None
CD: Common (>50%) |
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CD vs UC:
Ulcers / fissures |
UC: No fissures
CD: Deep, linear --> fissures |
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CD vs UC:
Lymphoid reaction |
UC: Mild
CD: Marked |
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CD vs UC:
Symptoms |
UC: Diarrhoea w/ blood & mucus; cramping; urgency/tenesmus
CD: Diarrhoea +/- blood; abdo pain (obstipation) |
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CD vs UC:
Perianal abscess/fistula |
UC: Rare (<25%)
CD: Common (75%) |
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CD vs UC:
Extraintestinal manifestations |
UC: Sclerosing pericholangitis, uveitis, arthritis, pyoderma gangrenosum (rare)
CD: Uveitis, arthritis |
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Causes of SBO:
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ABC'S EFGHIV:
Adhesions, abscess Bezoar (=foreign bodies) Cancer (neoplasms) Stricture Extrinsic (annular pancreas) Fibrosis (cystic) Gallstones Hernia Intuussusception Volvulus |
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Causes of LBO
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Adenocarcinoma / Neoplasia
Diverticulitis Volvulus In lumen: feces, bezoar In wall: stricture, Hirschprung's Outside wall: tumour, hernia, adhesions |
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Symptoms of bowel obstruction
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1) Colicky abdo pain
2) Vomiting: SBO=early, LBO=late 3) Distension: SBO=epi/hypogastric, LBO=generalized 4) Obstipation - SBO=late, LBO=early |
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Signs of bowel obstruction:
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Look: scars, hernia, abdo mass, distension, peristalsis
Feel.palpation: tendernesss Feel.percussion: hyper-resonant Listen: BS louder, more frequent & high pitched (tinkling) PR exam: feces, blood, mucus |
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What are the investigations for bowel obstruction?
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Supine and erect AXR, CXR
FBC, U&E Abdo CT SBS (Small bowel series) |
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What are the radiological features of SBO?
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"GAPS":
1) Gas absent in colon 2) Air fluid levels 3) Plicae circularae (ladder pattern) 4) Sentinel loops 5) String of beads (fluid filling) Position: Central |
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What are the radiological features of LBO?
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Picture frame pattern
Haustral markings (plicae semicircularis=extend only part way across lumen) Air-fluid levels Distension (proximal colon) Gas absent in rectum Position: Peripheral |
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What is the management of SBO?
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Conservative: Drip and suck
Surgical: LOA (lysis of adhesions), herniorrhaphy |
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Haemorrhagic loop of bowel caused by adhesions SBO
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Adhesion internal herniation of bowel contents bowel obstruction impaired venous drainage engorgement & haemorrhage impaired arterial flow infarction
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Small bowel obstruction
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Large bowel obstruction
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What is an ostomy? Stoma?
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Ostomy: GIT connected to the abdominal wall skin.
Stoma: The opening of the ostomy. Epitheliaisation (mucosa to skin) prevents closure |
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Difference between temporary and permanent stoma?
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Temporary = loop ileostomy/colostomy.
Permanent = end ileostomy/colostomy. |
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Indications for stoma?
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Temporary:
Protect anastamosis Divert stool from anorectum Caecal volvulus Permanent: Following colectomy if cannot anastamose Following removal of anorectum Severe faecal incontinence |
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Pre-op and post-op stomal care
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PRE-OP:
Education, counselling POST-OP: Input - Diet (no nuts, popcorn), NBM until peristalsis or POD2-5 Output - Normal=500-1000 mL/day Regular monitoring of viability Stomal remeasurement in 4/52 |
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Complications of stoma?
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Adhesion, abscess (parastomal)
Bleeding Constipation, osbtruction (SBO) Dehydration Stricture Fistula Herniation (parastomal) Ischaemia, ileus, infection, irritation of the skin Prolapse Retraction Ulceration (parastomal) Volvulus |
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Meckel's diverticulum
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WHAT? Solitary true diverticulum. 2 types of ectopic tissue (gastric + pancreatic)
WHY? Failure of involution of the vitelline duct (yolk sack to primitive midgut) WHERE? Anti-mesenteric side of the terminal ilium (within 2 feet of ileocecal valve) WHO? 2% of population, presents at age 2 |
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Complications and symptoms of Meckel's diverticulum
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Ulceration
(ectopic gastric mucosa) = bleeding or perforation Diverticulitis Resembles appendicitis Obstruction Volvulus or intussusception |
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Meckel's rule of 2's
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2% of population
2% symptomatic 2 y/o presentation 2 feet from ileocecal valve 2 inches long 2% symptomatic 1/2 will have ectopic tissue |
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Haemorrhoids aetiology?
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Dilated submucosal veins of the internal haemorrhoidal plexus
2o to venous pressure within haemorrhoidal plexus: - Constipation - Pregnancy (venous stasis) - Collaterals in portal HT |
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Haemorrhoids when looking at the lithotomy position.
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Classically situated @ 3,7,11 o'clock. (left lateral, right posterior, right anterior) >-
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Clinical features of haemorrhoids?
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"BUM Lump"
Bleeding - bright red, post-defacation Uncomfortable (discomfort), pruritis. (Uncomplicated=not painful, thrombotic/strangulated=severe pain) Mucus discharge (PR) Lump after defacation (palpable) |
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How are haemorrhoids described and graded?
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Location: External and Internal
External haemorrhoids: develop in inferior haemorrhoidal plexus, located below the anorectal (DENTATE) line = skin tags Internal haemorrhoids: dilation of the superior haemorrhoidal plexus. Grades 1-4 |
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How are internal haemorrhoids graded?
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Internal haemorrhoid grades
1: small haemorrhoids that bleed, but remain in rectum 2: prolapse on defecation/Valsalva & retract spontaneously 3: Prolapse on defacation/valsalve but require manual reduction 4: prolapse from anus, irreducible |
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In a 55 y/o pt w/ pPR bleeding & obvious haemorrhoids, what else must be excluded?
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Concomitant CRC
Altered bowel habit? Anaemia? Colonscopy & sigmoidoscopy essential. |
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Haemorrhoid banding
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Used to treat 2o, 3o internal haemorrhoids.
Forceps isolate and draw haemorrhoid into barrel of band ligator. Elastic band is released and occludes circulation to the haemorrhoid. Destruction via necrosis. Complications: Haemorrhage, sepsis, pain |
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Haemorrhoid treatments?
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Conservative:
Dietary fibre, local hydrocortisone and analgesia (topical or suppositories) Symptoms persist >4-6/52?... Surgery: Injection sclerotherapy by proctoscopy Infrared photocoagulation Haemorrhoidectomy (excision) |
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Complications of haemorrhoidectomy
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Haemorrhage
Infection Anal stenosis Fecal incontinence |
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Incisional Hernia
Portrusion of the pertinoeum and abdo contents into the subcutaneous plane through a defect at the surgical site scar |
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Incisional hernia
Signs and symptoms |
Symptoms:
Nagging discomfort Bulge Signs: Reducible lump Expansile cough impulse Accentuated by tensing the recti |
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Incisional hernia
Surgical Risk Factors |
Wound infection (most common)
Incision shape - T,V, angulated Incision location - Midline > Paramedian/upper > lower Devitalized tissue Suture material - Absorbable > non-absorbable |
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Incisional hernia
Patient risk factors |
Age
Obesity Systemic: DM, corticosteroids, malnutrition Local: Foreign body, haematoma, movement |
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Incisional hernia
Tx |
Surgically repaired
Reducible: Appose edges or mesh Irreducible: Open, mobilize, dissect; excise omentum Pre-op: weight reduction, PT, smoking cessation Post-op: Prophylactic AB, drainage |