• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

image

PLAY BUTTON

image

PLAY BUTTON

image

Progress

1/66

Click to flip

66 Cards in this Set

  • Front
  • Back
How to describe a path pot?
What organ?
Where?
What pathological process?
Aetiologic clues
Sequelae & complications
Incidental and related
DDx
How do you describe a lump?
1) Size
2) Site
3) Shape
4) Surface
5) Margins
6) Tenderness
7) Consistency
8) Composition: consistency, fluid thrill, transillumination, resonance, pulsatility
9) Mobility/fixation
10) Overlying skin
11) Regional lymph nodes
12) Other
What is the lesion?
Left: Pedunculated polyp
Right: Sessile polyp
What are the types of large bowel polyps?
Shape:
1) Sessile
2) Pedunculated
Aetiology
3) Neoplastic - adenomatous polyp (>100 = FAP, Gardner's syndrome)
4) Hyperplastic - delayed shedding
5) Inflammatory - IBD (UC, CD)
6) Hamartomatous - Peutz-Jegher's syndrome
Adenomatous polyps
7) Tubular (pedunculated)
8) Villous (sessile, malignant)

Risk of malignancy (adenoma to adenocarcinoma):
Polyp size (>2cm=50%)
Architecture: Villous 40%, tubulovillous 20%, tubular 5%
Severity of epithelial dysplasia
What are the risk factors for CRC?
FAP, HNPCC, Adenomatous polyps
FHX
IBD (esp. UC)
Diet, smoking, EtOH
DM, acromegaly
Low dietary fiber intake
Obesity, physical inactivity
Irradiation
What is the adenoma-carcinoma sequence?
Normal colonic epithelium  Hyperproliferative  Early Adenoma  Late adenoma  Carcinoma

- Ca develops from progressive accumulation of multiple genetic mutations

- Most cancers: Chromosomal instability pathway A
- HNPCC: Microsatellite instability pathyway B
What is the treatment for CRC?
Surgical resection:

5 cm margins.
Lymphovascular clearance (pericolic LNs)
Mesentary

Liver mets resected w/ 1-2cm margin + XRT/Chemo

XRT+Chemo only in rectal ca.
What is the treatment for a Ca at the hepatic flexure?
Right hemicolectomy

Caecum
Ascending colon
Part of transverse colon
Omentum
SMA branches: ileocolic, R colic, R branch of middle colic vessels

Anastamosis of lieum to transverse colon.
What is this lesion?
IBD.CD radiological features
4 S's

Stricture at the perianal ring
String sign = luminal narrowing @ distal ileum
Skip lesions = separation from surrounding loops
Sinus tract = communication between pathologic space and cavity
IBD.UC radiological features
"Lead pipe" colon = Loss of haustral markings
Shortening of colon
Toxic megacolon: dilated lumen (>6cm)
What is the lesion?
What are the perianal features of CD?
50% of CD patients
Skin tags
Fissures
Perianal sepsis
Anorectal strictures
CD vs UC:

Locations involved
CD: Any part of GI tract (mouth to anus)

UC: Colon only, rectum always involved
CD vs UC:

Rectal bleeding
CD: Uncommon

UC: Very common (90%)
CD vs UC:

Diarrhoea
CD: Less prevalent

UC: Freuqent small stools
CD vs UC:

Abdo pain
CD: Post-prandial / colicky

UC: Predefecatory urgency
CD vs UC:

Fever
CD: Common

UC: Uncommon
CD vs UC:

Palpable mass
CD: Frequent, RLQ

UC: Rare
CD vs UC:

Recurrence after surgery
CD: Common

UC: Rare
CD vs UC:

Histologic features
CD: Transmural distribution, focal inflammation, non-caseating granulomas, glands intact

UC: Mucosal distribution, diffuse inflammation, granulomas absent, gland destruction, crypt abscess
CD vs UC:

Endoscopic features
CD: Apthoid ulcerations, patchy lesions

UC: Diffuse erythemia, friability, loss of normal vascular pattern, continuous lesions
CD vs UC:

Radiologic features
CD: Strictures, fistula (=sinus tract), cobblestone mucosa, string sign (luminal narrowing), skip lesions

UC: Haustration loss, lead pipe appearance, shortening of colon, toxic megacolon (>6cm, dilated lumen)
CD vs UC:

Creeping mesenteric fat
UC: Not seen

CD: Common
CD vs UC:

Serosa
UC: Normal
CD: Granular, fibrosed or 'flared'
CD vs UC:

Depth of inflammation
UC: Mucosal (rarely submucosal)

CD: Transmural (full thickness)
CD vs UC:

Wall thickening
UC: Minimal, no fibrosis

CD: Common
CD vs UC:

Granulomas
UC: None

CD: Common (>50%)
CD vs UC:

Ulcers / fissures
UC: No fissures

CD: Deep, linear --> fissures
CD vs UC:

Lymphoid reaction
UC: Mild

CD: Marked
CD vs UC:

Symptoms
UC: Diarrhoea w/ blood & mucus; cramping; urgency/tenesmus

CD: Diarrhoea +/- blood; abdo pain (obstipation)
CD vs UC:

Perianal abscess/fistula
UC: Rare (<25%)

CD: Common (75%)
CD vs UC:

Extraintestinal manifestations
UC: Sclerosing pericholangitis, uveitis, arthritis, pyoderma gangrenosum (rare)

CD: Uveitis, arthritis
Causes of SBO:
ABC'S EFGHIV:

Adhesions, abscess
Bezoar (=foreign bodies)
Cancer (neoplasms)
Stricture
Extrinsic (annular pancreas)
Fibrosis (cystic)
Gallstones
Hernia
Intuussusception
Volvulus
Causes of LBO
Adenocarcinoma / Neoplasia
Diverticulitis
Volvulus

In lumen: feces, bezoar
In wall: stricture, Hirschprung's
Outside wall: tumour, hernia, adhesions
Symptoms of bowel obstruction
1) Colicky abdo pain
2) Vomiting: SBO=early, LBO=late
3) Distension: SBO=epi/hypogastric, LBO=generalized
4) Obstipation - SBO=late, LBO=early
Signs of bowel obstruction:
Look: scars, hernia, abdo mass, distension, peristalsis

Feel.palpation: tendernesss

Feel.percussion: hyper-resonant

Listen: BS louder, more frequent & high pitched (tinkling)

PR exam: feces, blood, mucus
What are the investigations for bowel obstruction?
Supine and erect AXR, CXR
FBC, U&E
Abdo CT
SBS (Small bowel series)
What are the radiological features of SBO?
"GAPS":

1) Gas absent in colon
2) Air fluid levels
3) Plicae circularae (ladder pattern)
4) Sentinel loops
5) String of beads (fluid filling)

Position: Central
What are the radiological features of LBO?
Picture frame pattern
Haustral markings (plicae semicircularis=extend only part way across lumen)
Air-fluid levels
Distension (proximal colon)
Gas absent in rectum

Position: Peripheral
What is the management of SBO?
Conservative: Drip and suck
Surgical: LOA (lysis of adhesions), herniorrhaphy
Haemorrhagic loop of bowel caused by adhesions  SBO
Adhesion  internal herniation of bowel contents  bowel obstruction  impaired venous drainage  engorgement & haemorrhage  impaired arterial flow  infarction
Small bowel obstruction
Large bowel obstruction
What is an ostomy? Stoma?
Ostomy: GIT connected to the abdominal wall skin.

Stoma: The opening of the ostomy.

Epitheliaisation (mucosa to skin) prevents closure
Difference between temporary and permanent stoma?
Temporary = loop ileostomy/colostomy.

Permanent = end ileostomy/colostomy.
Indications for stoma?
Temporary:
Protect anastamosis
Divert stool from anorectum
Caecal volvulus

Permanent:
Following colectomy if cannot anastamose
Following removal of anorectum
Severe faecal incontinence
Pre-op and post-op stomal care
PRE-OP:

Education, counselling

POST-OP:

Input - Diet (no nuts, popcorn), NBM until peristalsis or POD2-5
Output - Normal=500-1000 mL/day

Regular monitoring of viability

Stomal remeasurement in 4/52
Complications of stoma?
Adhesion, abscess (parastomal)
Bleeding
Constipation, osbtruction (SBO)
Dehydration
Stricture
Fistula
Herniation (parastomal)
Ischaemia, ileus, infection, irritation of the skin
Prolapse
Retraction
Ulceration (parastomal)
Volvulus
Meckel's diverticulum
WHAT? Solitary true diverticulum. 2 types of ectopic tissue (gastric + pancreatic)

WHY? Failure of involution of the vitelline duct (yolk sack to primitive midgut)

WHERE? Anti-mesenteric side of the terminal ilium (within 2 feet of ileocecal valve)

WHO? 2% of population, presents at age 2
Complications and symptoms of Meckel's diverticulum
Ulceration
(ectopic gastric mucosa) = bleeding or perforation

Diverticulitis
Resembles appendicitis

Obstruction
Volvulus or intussusception
Meckel's rule of 2's
2% of population
2% symptomatic
2 y/o presentation
2 feet from ileocecal valve
2 inches long
2% symptomatic
1/2 will have ectopic tissue
Haemorrhoids aetiology?
Dilated submucosal veins of the internal haemorrhoidal plexus

2o to venous pressure within haemorrhoidal plexus:
- Constipation
- Pregnancy (venous stasis)
- Collaterals in portal HT
Haemorrhoids when looking at the lithotomy position.
Classically situated @ 3,7,11 o'clock. (left lateral, right posterior, right anterior) >-
Clinical features of haemorrhoids?
"BUM Lump"

Bleeding - bright red, post-defacation
Uncomfortable (discomfort), pruritis. (Uncomplicated=not painful, thrombotic/strangulated=severe pain)
Mucus discharge (PR)

Lump after defacation (palpable)
How are haemorrhoids described and graded?
Location: External and Internal

External haemorrhoids: develop in inferior haemorrhoidal plexus, located below the anorectal (DENTATE) line = skin tags

Internal haemorrhoids: dilation of the superior haemorrhoidal plexus. Grades 1-4
How are internal haemorrhoids graded?
Internal haemorrhoid grades

1: small haemorrhoids that bleed, but remain in rectum

2: prolapse on defecation/Valsalva & retract spontaneously

3: Prolapse on defacation/valsalve but require manual reduction

4: prolapse from anus, irreducible
In a 55 y/o pt w/ pPR bleeding & obvious haemorrhoids, what else must be excluded?
Concomitant CRC

Altered bowel habit? Anaemia? Colonscopy & sigmoidoscopy essential.
Haemorrhoid banding
Used to treat 2o, 3o internal haemorrhoids.

Forceps isolate and draw haemorrhoid into barrel of band ligator. Elastic band is released and occludes circulation to the haemorrhoid. Destruction via necrosis.

Complications: Haemorrhage, sepsis, pain
Haemorrhoid treatments?
Conservative:
Dietary fibre, local hydrocortisone and analgesia (topical or suppositories)

Symptoms persist >4-6/52?...

Surgery:
Injection sclerotherapy by proctoscopy
Infrared photocoagulation
Haemorrhoidectomy (excision)
Complications of haemorrhoidectomy
Haemorrhage
Infection
Anal stenosis
Fecal incontinence
Incisional Hernia

Portrusion of the pertinoeum and abdo contents into the subcutaneous plane through a defect at the surgical site scar
Incisional hernia

Signs and symptoms
Symptoms:
Nagging discomfort
Bulge

Signs:
Reducible lump
Expansile cough impulse
Accentuated by tensing the recti
Incisional hernia

Surgical Risk Factors
Wound infection (most common)

Incision shape - T,V, angulated

Incision location - Midline > Paramedian/upper > lower

Devitalized tissue

Suture material - Absorbable > non-absorbable
Incisional hernia

Patient risk factors
Age
Obesity
Systemic: DM, corticosteroids, malnutrition
Local: Foreign body, haematoma, movement
Incisional hernia

Tx
Surgically repaired
Reducible: Appose edges or mesh
Irreducible: Open, mobilize, dissect; excise omentum

Pre-op: weight reduction, PT, smoking cessation

Post-op: Prophylactic AB, drainage