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13 Cards in this Set
- Front
- Back
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What vulvar precursor lesion is associated with smoking and HPV infection?
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Vulvar Intraepithelial Neoplasia
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What is the most common malignant neoplasm of the vulva?
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Invasive Squamous Cell Carcinoma, commonly preceded by VIN. Spreads stepwise to local lymph nodes first
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What non-neoplastic lesion causes thinning of the vulvar skin?
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Lichen Sclerosis. Can clinically mimic in-situ neoplasia.
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What is the screening test for Cervical Intraepithelial Neoplasia?
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Pap Smear. If abnormalities are detected a biopsy must be performed.
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What's one problem with a Pap smear?
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It has a fairly high false negative rate.
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What is the most fatal component of cervical cancer?
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Morbidity/mortality from cervical cancer is most commonly due to local effects: obstructed urteters, rectal fistula, etc. Renal failure and infection are common causes of death.
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Invasive carcinoma of the endometrium is typically of what type?
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Adenocarcinoma
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What is the primary risk factor for endometrial cancer?
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Increased estrogen. Obesity increases estrogen by peripheral conversion of androgens to estrogens.
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Where does endometrial cancer typically spread?
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* Pelvic lymph nodes
* Cervix/Vagina * Ovaries/peritoneum (uncommon) |
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What is the treatment for endometrial cancer?
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Hysterectomy.
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What is endometriosis?
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Endometrial glands outside the uterus.
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What are the clinical SXS of endometriosis?
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* Cyclical pelvic pain
* Bleeding/inflammation leading to masses, fallopian tubal obstruction * Infertility |
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A "benign smooth mm neoplasm of the uterus"?
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Leiomyoma (uterine fibroid)
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