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5 Cards in this Set

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What particle is moved through the urine more than any other?
urea
Explain how urea clearance is dependent upon diuresis, urine flow.
Higher flow rates prevent urea reabsorption and maintain high clearance. At lower flow rates, clearance drops, reabsorption increases, but concentration increases.
What compounds experience non-ionic diffusion?
weak acids and bases
What is diffusion trapped?
Charged molecules are trapped in the lumen
Explain the treatment of phenobarbital poisoning.
Give base and an osmotic diuretic and hydrate to reduce ADH secretion.

This will diffusion trap the molecule.
HPb is converted to Pb- in the lumen.