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107 Cards in this Set
- Front
- Back
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bone tissue is also called _____ tissue
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osseous
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the skill, spinal column, and thoracic cage make up the ____ division of the skeleton.
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axial
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by shape, most cranial bones, the sternum, and the scapulae are classified as ____ bone.
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flat
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Histological examination reveals 2 types of bone: _____ and ______ bone
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compact and spongy.
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_______ bone which forms the surface of all bones.
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compact
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_______ bone is found within the bodies of the vertebra and heads of the the long bones.
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spongy
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In life, a bone is covered with a very tough fibrous sheath called the _______.
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periosteum
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the bone-forming cells that synthesize its matriz and later become trapped in it are called.
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osteoblasts.
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most lamellae of compact bone are concentrically arranges around a space called the?
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centeral canal.
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blood is produces in a tissue of the skeletal system called the ______.
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red bone marrow.
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_________, which digests collagen in bone matrix, is secreted by osteoclats.
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acid phosphates.
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During the process in acid phosphates, chondrocyes in the zone of _______ enlarge, and the walls of the matrix between their lacunae become very thin.
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cell hypertophy
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the growth zone of a child's femur- a cartilaginous region between the shaft and head of the bone is called the ________.
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ephyiseal plate
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The structure of a bone is determined by the mechanical and gracitational forces applied to that bone is what?
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Wolff's Law
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A deficiency of calcium in the blood, called _____, can lead to sustained muscle contractions called _____.
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hypocalcemia; tetany.
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Calcium homeostasis in adults is maintained almost entirely by the secretion of ______, which regulates the activity of bone-dissolving cells called ________.
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parathyroid hormone; osteoclats
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The most common adult bone disease, especially among postmenopausal white women, is ________.
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osteoprosis.
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what occupy the lacunae of compact bone?
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ostocytes
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Bones that develop within the tendons sometimes after birth?
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sesamoid bones
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region of long bone made of compact bone with central meduallary cavity?
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diaphysis
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Layer of hyaline cartilage on the end of a long bone
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articular cartilage
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Bone-dissolving macrophages with ruffled borders.
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osteoclasts
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cells that release RANKL
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osteoblasts
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contain the nearest blood vessels to most osteocytes in compact bone
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central canal
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describes the function of red bone marrow
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hemopoietic
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mode of ossification that produces the flat cranial bones
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intramembranous
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the only method by which mature bones can grow.
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appositional
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what causes excessive sensitivity in nervous and muscle tissue
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hypocalcemia
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during ossification of the humerus, ________ hypertrophy and die.
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chondrocytes.
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the patella is an example of
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a sesamoid bone
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Calcitroil (vitamin D)synthesis involves all of the following except: a) ultraviolet light b) cholesterol ; c) the kidneys; d) the liver; e) osteoblasts
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E
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the process in which hyaline cartilage is converted to bone is called _______ ossification.
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interstitial
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calcitriol functions in:
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increasing calcium absorption by the small intestine.
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one example of ectopic ossification is?
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atherosclerosis
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A pit in the surface of a bone is called?
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a fovea
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A rough area on a bone, usually serving for muscle attachment, is
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a tuberosity
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the diaphysis of a 35-year old's femur is normally filled with
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yellow marrow
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tetany, laryngospasm, and suffocation could result from:
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lack of parthyroid hormone
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a healing fracture exhibits, at one stage, ________ containing collagen and patches of fibrocartilage.
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a soft callus
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the relative concentration of calcium and phosphate ions must reach a critical value, the solubility product, in order:
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for bone deposition to occur.
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the carpals are bones in the:
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wrist
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the head of a long bones is called the
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epiphysis
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the fusion of blood monocytes gives rise to:
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osteoclasts
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blood vessels of the periosteum enter the bone matrix by way of:
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perforating canals
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in endochondral ossification of the metaphyses of a long bone, the zone of _______ is the area where chondrocyes quit dividing and increase in size.
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hypertrophy
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Action potentials are propagated to the interior of a muscle fiber by extensions of the sarcolemma called the
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T tubels
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the _________serves as a reservoir of calcium ions in skeletal muscle.
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terminal cisteria of SR
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The thick myofilaments are composed of the protein ________.
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myosin
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The synapse where a motor nerve fiber and muscle fiber meet is called
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neuromuscular junction.
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motor nerve fibers stimulate skeletal muscle fibers with a neurotransmitter called
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acetycholine (ACh)
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a skeletal muscle fiber has a resting potential of about -90 mV, called its ______, across the sarcolemma.
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resting membrane potential
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When a muscle fiber is excited, its membrane produces a brief, self-propagating voltage change called a
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action potential
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currently, our best understanding of how muscle contracts is called the __________.
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sliding filaments theory
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myosin cannot bind to actin until calcium binds to _________ and __________ moves out of the way of the active sites on the actin.
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troponin, tropmysion.
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when a muscle is stimulated so frequently it can't completely relax between twitches, the successive twitches become stronger and stronger, this is called.
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incomplete tetanus.
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in ________ contraction, a muscle develops or maintains tension even as it is being stretched, thus preventing it from relaxing too quickly and producing abrupt, uncoordinated actions.
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eccentric
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the difference between one's normal rate of oxygen consumption and the rate seen at the end of a strenuous exercise is called _________.
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oxygen debit.
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In_____________ smooth muscle, neighboring muscle cells are joined by gap junctions, and stimulate each other to contract.
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single unit.
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most sympathetic nerve fibers stimulate smooth muscle contraction via the neurotransmitter.
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norepinephrine.
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structure that define the limits of a sarcomere
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z discs.
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End product of anaerobic fermentation partly responsible for muscle fatigue
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lactic acid
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Calcium-binding protein of the thin myofilament
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troponin
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calcium-binding protein of the sarcoplasmic reticulum
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calsequestrin
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source of energy for muscle contraction
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glycogen
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location of acetylcholinestease
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synaptic cleft
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movement of thin filament past thick filament in sarcomere
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power stroke
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sustained muscle contraction at a high-stimulus frequency
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tetanus
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shortening of a muscle while maintaining constant tension
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isotonic contraction
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provides energy for short bursts of skeletal muscle activity
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phospahagen system
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what catalyzes the transfer of P one from CP to ADP
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Creatine Kinase
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Which of the following is not found in the thin filaments of skeletal muscle?
a) F actin b) ATPase c) troponin d) tropomysion e) Ca 2+ receptors |
B
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In contrast to slow oxidative muscle fibers, fast glycolytic fibers:
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fatigue more quickly
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when a muscle develops tension but does not shorten, it is said to exhibit
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isometric contraction
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Endurance training has the least effect on the
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thickness of muscle fibers
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Autonomic nerve fibers release neurotransmitters from varicosities in
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single-unit smooth muscle
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In order for a skeletal muscle to relax, _______ must be enzymatically degraded
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ACh
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In skeletal and cardiac muscle, actin and myosin overlap in the ________ of a sarcomere
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dark bands
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a skeletal muscle fiber has more _____ than it does any of these other features.
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sarcomeres
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when there is not enough oxygen to produce ATP by aerobic respiration,a muscle fiber can produce some ATP by borrowing phosphate groups from:
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creatine phosphate
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what is present in smooth muscle myocytes but not in myofibers of skeletal muscle?
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calmodulin
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what does this refer to? when one nerve fiber and all the muscle fibers it innervates
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motor unit
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Actin is lacking from the ________ of a relaxed sarcomere.
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H bands
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based on the sliding filament theory, we would expect __________ during skeletal muscle contraction .
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the I bands get shorter and A bands to remain the same.
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the -90 mV membrane potential of a resting skeletal muscle cell results primarily from the
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presence of large non diffusible anions in the ICF
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what are the six functions for the skeletal system?
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support, protection, movement, electroylte balance, acid-base balance, and blood formation.
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osseous tissue is a connective tissue in which the matrix is hardened by mineral depostion called
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mineralization
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the bones support the body and its structures
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support
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bones enclose and protect organs
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protection
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the action of muscles on bones produces movement
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movement
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the skeleton stores calcium and phosphate and releases them as needed.
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electrolytes balance
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bone tissue buffers the blood by abosrbing or releasing alkaline salts such as calcium phosphate
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acid-base balance
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red bone marrow is the major producer of blood cells, both red and white.
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blood formation.
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blood vessels penetrate into the bone through tiny holes called
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nutrient foramina.
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other collagen fibers of the outer layer penetrate into the bone matrix as
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Sharpey fibers
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_____________ is important to bone growth and fracture healing.
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osteogenic layer.
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the internal surface of a bone is lined with _____________.
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endosteum
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the spongy layer is called
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diploe
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_________ are stem cells that give rise to most other bone cells.
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osteogenic cells
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___________ are bone forming cells
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osteoblasts
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___________are former osteoblasts that have become trapped in the bone matrix they depostited.
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Osteocytes.
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osteocytes cells reside in cavities called__________, connected by slender channels called ________.
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lacunae.canaliculi
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Osteocytes function is to
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resorb or deposit bone matrix.
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____________ are bone-dissolving cells found on the bone surface.
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osteoclasts
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_________ develop from bone marrow stem cells that give rise to blood cells
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osteoclasts
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the matrix or osseous tissue is about 1/3 _________ and 2/3 _________ matter.
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organic and inorganic.
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_______ matter includes collagen and protein-carbohydrate complexes.
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organic
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bones in a class of materials is called
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composite
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