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10 Cards in this Set
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- Back
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Thrombosis
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A thrombus is an intravascular mass attached to the vessel wall and is composed of varying proportions of coagulation factors, RBCs, and Platelets.
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What is the pathogenesis of thrombrosis?
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-Endotheial Cell Injury
-Stasis of Blood Flow -Hypercoagulability |
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What are the types of thrombi?
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-Venous Thrombi
-Arterial Thrombi -Postmortem Clot |
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What is the pathogenesis of Venous Thrombi?
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-Stasis
-Hypercoagulable State |
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What is the most common site of thrombotic origin?
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Deep vein in the lower extremity below the knee.
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What other sites during thrombi originate?
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-Superficial Saphenous
-Hepatic veins -Renal Veins -Dural Sinuses |
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What is the composition of thrombi?
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-Adherent occlusive, dark red fibrin clot
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Where do thrombi from the lower extremities propagate to to? What is the danger of this?
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a) They propagate toward the heart.
b) The danger is pulmonary artery embolization. |
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What prevents the formation of venous thrombi?
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Anticoagulants, such as heparin and warfarin prevent formation of venous thrombi.
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What is the pathogenesis of arterial thrombi?
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-Endothelial cell injury due to turbulent blood flow. Platelets adhere to areas of injury.
-Hypercoagulable state |
