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17 Cards in this Set
- Front
- Back
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What does peroxidase do in the thyroid?
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aids in the iodination of tyrosine residues on thyroglobulin to synthesize thyroid hormone
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What is Hashimoto’s disease?
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autoimmune hypothyroidism
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What is Grave’s disease?
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autoimmune hyperthyroidism
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What is the main drug used to treat hypothyroidism?
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Levothyroxine
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Which would have a faster onset of action, levothyroxine or liothyronine?
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liothyronine
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Which causes a goiter, iodine deficiency or hyperthyroidism?
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Both
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What is the main side effect of thiocyanate?
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aplastic anemia
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What is the mechanism of action of 131I in treating hyperthyroidism?
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radioactive destruction of some thyroid tissue.
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What is the biggest side effect of 131I?
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hypothyrodism
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Potassium iodide would be used to treat hashimotos’s disease or grave’s disease
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Grave’s disease
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What is the main mechanism of action of iodide salts in treating hyperthyroidism?
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high levels inhibit the secretion of thyroid hormone
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What would you use to control a case of hyperthyroidism before a surgical removal of part of the thyroid gland?radioactive iodide, high concentrated iodide salts, methimazole
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high concentrated iodide salts, methimazole
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What agent would work rapidly to control a thyroid storm?
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high concentrated iodide salts
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What is the mechanism of action of propylthiouracil in treating hyperthyroidism?
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blocks the peroxidase catalyzed reactions to inhibit thyroid hormone synthesis
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Which has a faster onset of action, Lugol’s solution or methimazole?
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Lugol’s solution
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What are some of the side affects of propylthiouracil?
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Pruritic rash, arthralgias, hypoprothrombinemia, agranulocytosis
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Which agent would you most likely use to treat hyperthyroidism during pregnancy?
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propylthiouracil
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