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38 Cards in this Set

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  • Back
colloid
eoinophilic proteinaceous material in thyroid
secretion of thyroid hormones is controled by
TSH (pit)
controlled by secretion of TR (HT)
thyroid hormone secretion operates via
negative feedback loop
thyroid hormones are active
when not bound
they stimulate metabolism in general
most congenital abnormalities of thyroid develop secondary to
migration problems during embryogensis
lingual thyroid
thyroid material left at base of tongue
if thyroid tissue left between gland and tongue it become
cystic,
thyroid duct cyst
complete absence of thyroid gland
hypothyroidism and leads to developmental problems and retardation
hyperthyroidism
excess thyroid hormone
hypermetabolic state
tachycardia
sweating
weight loss
oligomenorrhea
fine hair
EXOPHTHALMOS
hyperthyroidism is almost always caused by
abnormal thyroid stimulater (graves disease)
or neoplasm
most frequent cause of hyperthyroidism
graves disease
IgG ab agonisits to TSH receptor
hypothyroidism is characterized by
myxedema, boggy appearing sking
bloated
depression
lethargy
sensory dfects
most common form of thyroiditis
autoimmune or Hashimoto
secondary to stim of cytotoxic t cells and b cells
most common neoplasm of thyroid
follicular adenoma
benign
F:M 7:1
no vascular invasion or extra capsular extension
most common malignancy of thyroid gland
papillary carcinoma
pt rarely die even with mets
psammoma bodies
papillary carcinoma
nuclear enlargement, overlap, orphan annie eyes, nuclear pseoinclusions
dx features of papillary carcinoma
fllicular carcinoma
thyroid malignancy
hematogenous spread, no lymph node involvement
behave poorly
anaplastic carcinoma
10% thyroid malignancy,
rare, aggressive, invasive, UNVERSALLY FATAL
universally fatal thyroid malignancy
anaplastic carcinoma
tumor of thyroid that secretes hormone
meduallry carcinoma
three major classes of antidotes
removers
consequence treaters
true antidotes
activated charcoal
removal antidote
thiamine
treats consequence of alcohol abuse malnutrition
glucagon
reverses dysrythmias and hypotension if fail to respond to atropine, epii, after beta blocker or ca cha blocker od
methylene blue
clears methemoglobin after NO or lidocain od
NaBicarb
reverse acidosis
Clonidine
alpha2 aonist relieve opiod withdrawal symptoms
Folic acid/leucovorin
reverses malnutrition associate with methanol intox
hyperbaric oxygen
CO poisoning
heavy metal chelator
true antidote
anti digoxin antibody
binds digoxin, inhibits associate with cardia receptors
reverses efects of opiates
naloxone
acetominohen antidote
N acetylcystein
methanol or ethylene glycol
ethanol
alcohol dehydrogenase inhibitor
4 methylpyraole
organophosphate pesticeide
pralidoxime
benzodiazapine OD
flumazenil