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16 Cards in this Set
- Front
- Back
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What is xylitol used for?
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Sugar substitute
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What is the mode of action of xylitol toxicity in dogs?
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Strong promoter of insulin release and can cause severe hypoglycemia
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**When do signs of xylitol toxicity begin to appear in dogs?
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As quickly as 30 minutes after ingestion- see sudden decrease in blood glucose
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*What is usually the first sign of xylitol toxicity?
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Vomiting
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What is the main organ of xylitol metabolism?
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Liver
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What is the mechanism of liver necrosis from xylitol toxicity? What are the sequelae?
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Unknown
Severe necrosis---> secondary impaired clotting factor production & DIC--> hemorrhage & often die |
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When are elevated liver enzymes detected in some dogs with xylitol toxicity?
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8-12 hours
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Animals with hepatic injury from xylitol consumption usually become acutely ill in about ______ hours.
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48
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What is the treatment for xylitol toxicity?
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No antidote!!!!!
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What is 2,4-dichlorophenoxyacetic acid used for?
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Common systemic pesticide/herbicide used in control of broadleaf weeds
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**What is the most common source of 2,4-D poisoning?
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Almost always due to accidental ingestion of concentrates or discarded excess or pooled sprays
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**What are the primary clinical signs of 2,4-D toxicity?
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Neurological
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What are the best specimens for laboratory confirmation of 2,4-D toxicity?
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Plasma or serum
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What is the treatment of 2,4-D toxicity?
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No specific antidotes
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What is the prognosis of 2,4-D toxicity?
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Unless severe CNS depression, recovery should be rapid
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How are 2,4-D and canine lymphoma related?
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Found that dogs in homes where lawns were treated with 2,4-D were twice as likely to develop malignant lymphoma
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