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8 Cards in this Set
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What are the sources of soluble oxalates?
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plants that contain large amounts such as pigweed, beet,lamb quarters, halogeston, sorrel, rhubarb, greasewood
K and Na oxalates are found in household and industrial products such as rust removers, bleaches and tanning compounds |
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What is the toxicity of soluble oxalates?
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sheep may be poisoned by .55% of body weight - .1% if starving
non fatal toxic dose in adult horses is 200g/day for 8 days toxicity is highest in the leaves |
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What is the mechanism of action of soluble oxalates?
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combine with calcium ion to form calcium oxalate
leads to hypocalcemia - affects bone and milk production precipitation of calcium oxalate crystals in kidney tubules causing kidney damage and necrosis |
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What are the clinical signs of soluble oxalate toxicosis?
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colic, dullness, depression, muscle twiching and muscles weakness
rapid breathing and blood tinged froth around the mouth |
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What are the lesions associated with soluble oxalate?
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excess fluid in abdominal and thoracic cavities
emphysema -froth in mouth and esophagus kidneys show dark red cortex and medulla separated by a gray line from crystals |
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How do you laboratory diagnose soluble oxalates?
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presents of Ca oxalate crystals in the kidney
hypocalcemia high BUN |
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What are the differential diangoses of soluble oxalates?
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rumen acidosis
milk fever hypocalcemia |
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How do you treat soluble oxalate toxicity?
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activated charcoal or lime water to prevent absorption
Calcium gluconate IV slowly may cause transit improvement but not curative saline -glucose to treat alkalosis and cause diuresus -supplementation of calcium salts supportive therapy for nephrosis |
