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11 Cards in this Set
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- Back
- 3rd side (hint)
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Rb (13q)
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Retinoblastoma, osteosarcoma
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Rb gene product blocks G1 --> S phase of the cell cycle |
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p53 (17p)
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Most human cancers, Li-Fraumeni syndrome
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p53 gene product blocks G1 --> S phase of the cell cycle |
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BRCA1 (17q)
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Breast and ovarian cancer
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DNA repair protein |
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BRCA2 (13q)
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Breast cancer
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DNA repair protein |
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p16 (9p)
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Melanoma
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APC (5q)
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Colorectal cancer (associated with FAP)
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WT1 (11p)
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Wilms' tumor
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NF1 (17q)
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Neurofibromatosis type 1
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NF2 (22q)
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Neurofibromatosis type 2
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Type 2 = 22 |
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DPC (18q)
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Pancreatic cancer
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DPC--Deleted in Pancreatic Cancer. |
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DCC (18q)
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Colon cancer
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DCC-Deleted in Colon Cancer. |
