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84 Cards in this Set

  • Front
  • Back
Are most calcifications benign or malignant
benign
What are the 2 most important characteristics to determine when analying breast calcificiations
morphology and distribution
What is the ddx of a typical benign calcification (birads 2)
7
calcifications with radiolucent center
milk of calcification
vascular calcification
popcorn calcifications
large rod like calcification
round calcification
FB injection granuloma
What is large rod like calcification associated with
duct ectasia
What are some types of calcifications that may have a radiolucent center
lucent centered calcification
egg sheel or rim calcification
skin calcification (sometimes)
dystrophic calcification (sometimes)
What are the characteristics of 'lucent centered calcifications'
5
variable size
round or oval
smooth surfaces
lucent centers (obviously)
walls are thicker than eggshell/rim type
What are lucent centered calcifications associated with
fat necrosis or calcified debris in ducts or oil cyst
What are the characteristics of eggshell/rim calcifications
smaller than 1mm in thickness
What are eggshell/rim calcifications associated with
fat necrosis and oil cyst (like calcificaton with lucent center)
What does a rim calcification/egg shell represent
calcification deposit on the surface of a sphere
can an oil cyst be either 'lucent centered calcificaton or an eggshell/rim calcification
yes (depends on the thickness of surrounding calcs)
Where is the MC location of skin calcifications
inframammary fold, parasternal axilla, and areola
How do you diagnose skin calcifications
tangental view
Do skin calcifications typically have a radiolucent center
yes
When are dystrophic calcifications typically seen
2
irradiated breast
s/p trauma
What are the mamographic charateristics of dystrophic calcifications
irregular
larger than 0.5mm
often have lucent centers
If fat necrosis calcifies what does it look like
rim calcifications and with time will become thicker an more like
dystrophic calcifications
What is the birads category of fat necrosis or oil cyst
Birads 2
What type of calcifications is sometimes assoicated with biopsy
dystrophic calcifications in the plane of biopsy
What do you do if you are unsure if calcifications are benign or malignant
birads 3 and fu in 6 months
Calcifications with radiolucent center
4
lucent centered calcifications
egg shell or rim
skin calcifications (sometimes)
dystrophic calcificatons (sometimes)
What is milk of calcium calcificationss
sedimetnted calcifications in macro or microcyst
What is the appearance of MOC calcifcations on the lateral view
more clearly defined
semilunar
crescent shaped
curvilinear or linear
What is the appearance of MOC calcifications on CC view
less evident and appears fuzzy
round
amorphous deposits
What is the most important characteristic of MOC calcifications
change in shape of calcifications on different views
What are the typically benign calcifications covered so far
calcifications with radiolucent centers (and subtypes)

MOC calcifications

(now vascular calcifications)
Describe vascular calcifications
parallel tracks
linear callcifications associated with tubular structure
When do you want to report vascular calcifications
women less than 50 (increased risk of CAD)
What are the typically benign calcification covered so far
calcifications with radiolucent centers (and subtypes)

MOC calcifications

vascular calcifications

(now coarse or popcorn calcifications)
Describe popcorn like calcifications
classicaly large greater than 2-3mm in diameter
What is the MCC of popcorn like calcifications
involuting fibroadenomas
What is typical location of the calcification of an involuting fibroadenoma
eccentric
What is the ddx for a heavily calcified mass
involuting fibroadenoma
cacified hematoma
fat necrosis
What is the work up for a heavily calcified mass
it is benign and no further work up required
If there is a mass that has faint calcifications that are more central in location what is the work up
biopsy
What are large rod-like calcifications associated with
duct ectasia
What are the characteristics of large rod like calcifications
3
solid or smooth linear rods
radiate towards the nipple
occasionally branch
Can large rod like calcifications (ductal ectasia) have lucent centers when calcium forms in the duct walls
yes
Is ductal ectasia usually bilateral
yes
When is ductal ectasia typically seen
women older than 60y
What are the two types of ductal ectasia
intraductal

periductal (lucent centers?)
What is more common intraductal or periductal ectasia
intraductal
If there is rod like calcifications in one breast do you continue a work up
yes
IS round calcifications another type of benign calcificaitons
yes
Describe findings of benign round calcifications
variable size (small and punctate)
scattered
If round calcifications are clustered what should be done
close surveillance or biopsy (especially if new or ipsilateral to cancer)
What are the typically benign calcifications we have covered
calcifications with a lucent center (and sub categories)
MOC calcifications
Vascular calcifications
Coarse/Popcorn
large rod like (duct ectasia)
round calcification
(now FB injection granuloma)
What are some causes of FB injection granuloma
2
silcone
parafin
Are FB injections granulomas bilateral
yes (inject both breast btw this is uncommon bc illegal in US)
What category are typically benign calcifications
birads 2
What are the intermediate concern (suspicious calcifications) birads 4
amorphous or indistint calcifications
Describe the characteristics of Amorphous or indistinct calcifications (this is intermediate or suspicous calcifications)
small hazy in appearance that is difficult to discern
Can diffuse scattered amorphous calcifications usually be dismissed as benign
yes (with the help of mag views)
If there is clustered, regional, linear or segmental distribution of amorphous calcifications should you biopsy
yes
Beside amorphous calcifications what is another intermediate concern/suspicous calcification
(birads 4)
coarse heterogenous
Describe coarse heterogenous calcifications
irregular, conspicuous calcifications that are generaly larger than 0.5 mm and tend to coalesce but are not the size of irregular dystrophic calcifications
What is the size of a coarse heterogenous calcification
generally greater than 0.5mm
What are coarse heterogenous calcifications associated with
4
malignancy
fibrosis
fibroadenomas
post trauma
How is heterogenous calcification differentiated from coarse dystrophic calcifications
tend to coalesce
smaller
What are the 2 birads 4 category calcifications
amorphous
coarse heterogenous
What category are fine pleomorphic calcifications
category 5
Describe the findings of fine pleomorphic calcifications

(correct prior slide these are birads 4-5)
variable size and shape
less than 0.5cm in diameter
What are the 2 high probabitly calcifications patterns for malignancy
Fine pleomorphic
Fine linear or fine branching calcifications
Describe fine linear/branching calcifications
thin, linear or curvlinear irregular calcifications which may be discontinous and are smaller than 0.5mm width
What does the finding of fine linear/branching calcifications suggest
filling of lumen or duct involved with cancer
What are fine pleomorphic and fine linear/branching calcs birad category
4 or 5
What is the calcifications of a fibroadenoma
popcorn (birads 2)
Are coarse heterogenous calcifications suspicious
yes birads 4
What is diffuse or scattered calcification
randomly throughout the breast
If there is punctate and amorphous calcifications though out the breast what is the birads category
B2 (likely benign)
What is the definition of regional calcifications
scattered in a large volume (>2cc) of breast tissue not conformed to a duct distribution
What is the definition of grouped or clustered calcificatios
at least 5 calcifications occupying a small volume (less than 1 cc) of tissue
What is linear distribution of calcifications
calcifications that are arrayed in a line (this may raise suspicioun as it suggest ductal distribution)
What should linear distribution be differentiated from
vasclular calcs
Do linear calcifications warrant biopsy
yes
What do you do if you have a round (non-suspicious) morphology and a supsicious (linear) distribution
go with the higher suspicious feature and biopsy
What is segmental distribution
calcifications in a lobe or segment of breast
Is segmental distribution worrisome
yes suggest deposits in ducts and their branches
Are both linear and segmental distribution of calcifications worrisome
yes
What Birads category is probably benign
birads 3
What type of calcifications go in the birads 3 category
round or punctate
What is the classifications of round or punctate calcifications in a linear or segmental distribution
birads 4 (bc of suspicous distribution)
If you have round or punctate calcifications what should be done
further work up with mag views
can round and clustered calcifications undergo survailence
yes ??