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76 Cards in this Set
- Front
- Back
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Epinephrine
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α,β-agonist
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Norepinephrine
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α,β₁-agonist
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Phenylephrine
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α₁-agonist
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Oxymetazoline
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α₁-agonist
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Methoxamine
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α₁-agonist
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Midodrine
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α₁-agonist
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Clonidine
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α₂-agonist
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Methyldopa
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α₂-agonist
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Guanabenz
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α₂-agonist
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Guanfacine
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α₂-agonist
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Isoproterenol
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β-agonist
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Dobutamine
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β₁-agonist
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Albuterol
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β₂-agonist
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Ritodrine
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β₂-agonist
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Terbutaline
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β₂-agonist
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Metaproterenol
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β₂-agonist
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Salmeterol
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β₂-agonist
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Amphetamine
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NE Releasing Agent
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Methylphenidate
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NE Releasing Agent
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Tyramine
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NE Releasing Agent
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Dopamine
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NE Releasing Agent, D-direct
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Ephedrine
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NE Releasing Agent, general effector
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Pseudoephedrine
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NE Releasing Agent, general effector
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Phentolamine
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α-antagonist
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Phenoxybenzamine
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α-antagonist (irreversible)
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Prazosin
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α₁-antagonist
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Terazosin
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α₁-antagonist
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Propranolol
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β-antagonist
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Timolol
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β-antagonist
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Pindolol
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β-antagonist
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Atenolol
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β₁-antagonist
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Bisoprolol
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β₁-antagonist
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Metoprolol
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β₁-antagonist
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Esmolol
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β₁-antagonist
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Labetalol
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α₁,β-antagonist
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Acetylcholine
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M,N-agonist
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Carbachol
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M,N-agonist
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Muscarine
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M-agonist
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Bethanecol
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M-agonist
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Pilocarpine
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M-agonist
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Physostigmine
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AChE blocker (reversible)
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Neostigmine
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AChE blocker (reversible)
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Demecarium
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AChE blocker (reversible)
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Edrophonium
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AChE blocker (reversible)
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Isoflurophate
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AChE blocker (irreversible)
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Echothiophate
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AChE blocker (irreversible)
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Pralidoxime
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AChE rescuer
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Botulinum toxin
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ACh Release Inhibitor
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Atropine
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M-antagonist
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Nicotine
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Ganglionic blocker (depolarizing)
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Warfarin
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Albumin-bound, idiosyncratic effects due to activity levels of vit. K reductase.
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Digitoxin
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Albumin-bound
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Diazepam
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Albumin-bound
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Cimetidine
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CYP-inhibitor
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Phenobarbital
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CYP2, CYP3 inducer, bishydroxycoumarin metabolism increased
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Glucocorticoids
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CYP3 inducer
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Rifampin
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CYP3 inducer
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Clofibrate
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CYP4 inducer
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Primaquine
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Type II (cytolytic) allergy, idiosyncratic effects due to deficiency in G6PD, black males.
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Choline
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Used to synthesize acetylcholine.
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Creatinine
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Used to estimate GFR.
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Cyclic-AMP
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Second messenger in Gs/Gi pathway, activates PKA.
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Cyclic-GMP
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Second messenger in enzyme-linked pathway, activates PKC.
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GABA
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Neurotransmitter, ion channel ligand.
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Gentamicin
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Antibiotic, 17 L volume of distribution.
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Glutamate
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Neurotransmitter, ion channel ligand.
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Glycine
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Neurotransmitter, ion channel ligand.
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Hexamethonium
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Ganglionic blocker, neuronal nicotinic receptor antagonist.
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Isoniazid
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Idiosyncratic effects due to inherited deficiency in metabolism.
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Morphine
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Example of molecular mimicry?
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Body volumes (70 kg male)
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42L - TBW
14L - ECF 6L - Blood 3L - Plasma |
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Nitric oxide
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Neurotransmitter, triggers cGMP.
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Substance P
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Neurotransmitter, GPCR receptor
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Succinylcholine
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Idiosyncrasy in plasma cholinesterase levels.
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Vitamin D
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Idiosyncrasy in vit. D resistant rickets.
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Tyrosine kinase
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Enzyme-linked receptor.
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