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41 Cards in this Set

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Delirium & cognition
-reduced ability to differentiate sensory information from hallucinations, dreams, illusions, imagery
-fragmented & disorganized thinking - unable to reason, judge, abstract, solve problems
- unable to form memories or store & retrieve info
delirium & attention/wakefulness
-difficulty with: alertness, selectiveness, directiveness
-wakefulness reduced during day, leading to naps & drowsiness
-sleeplessness, agitation at night
delirium & psychomotor behavior
-alternates between hyperactive & hypoactive
-slurred & disjointed sleep, aimless vocalizations & repetitions
-groping/picking at bedclothes, sudden movements
delirium & emotional disturbances
-fear, anxiety, irritability, anger, euphoria, apathy
delirium onset
-acute, over hours or a few days
-especially common in children & after age 60
delirium course
-fluctuates
-symptoms usually worse at night
delirium duration
may resolve in a few hours - few weeks
delirium outcome
recovery if underlying disease is corrected or self-limiting
delirium etiologic factors
-systemic infections
-metabolic disorders (hypoxia, hepatic or renal disease, hypoglycemia)
-postoperative states
-substance intoxication& withdrawal
-head trauma
depression characteristics
-dysphoric mood ranging from mild, transient feelings of sadness to a severe sense of helplessness & hopelessness
-loss of interest in usual activities
-appetite & sleep disturbances
-difficulty concentrating/thinking
-decreased energy
-feelings of anxiety, irritability, fear, brooding
depression onset
-able to date with some precision
-variable; symptoms usually develop over period of days to weeks but may be sudden
depression course
-often not recognized or misdiagnosed in older adults
-can be masked by symptoms of dementia (disorientation, memory loss, apathy, inattentiveness)
depression duration
-self limiting
-median time period is 8 months; may last up to 2 years
depression outcome
-can be successfully treated
-spontaneous recovery is expected
-severe may end in suicide
depression etiologic factors
-situational: bereavement, loss of health, major catastrophic event, trauma
dementia characteristics
-memory impairment
-aphasia,apraxia,agnosia
-decline in occupational/social functioning
-spatial disorientation, poor judgment
-violence, suicidal behavior
-slurred speech, anxiety, mood & sleep disturbances
-delusions, hallucinations
dementia onset
-depends on underlying etiology
-may be sudden (head trauma) or slow
-progress is relentless over several years
dementia course
-depends on underlying etiology
dementia duration
-may progress to death over several years
-may be slowed
dementia outcome
-generally irreversible
aphasia
loss of language ability
agnosia
-loss of sensory ability to recognize objects
-initially, can't recognize everyday objects. in later stages, can't recognize loved ones or body parts
apraxia
-loss of purposeful movement without loss of muscle power
-ability to conceptualize/perform motor tasks deteriorates
see box 14-1, Kneisl p. 303 for behavioral changes of DAT
right now
early stages of DAT mini mental score
>18
moderate DAT mini mental score
12-18
severe DAT mini mental score
<12
Dementia with Lewy Bodies (DLB) pathophys
-lewy bodies are abnormal concentrations of protein that develop inside nerve cells
DLB manifestations
-parkinsonian features
-persistent or recurrent visual hallucinations
-fluctuating cognition
Vascular dementia
-rapid onset
-one-sided weakness, emotional outbursts, stepwise rather than progressive decline in intellectual functioning
-history of HTN, diabetes, cardio disease
Parkinson's disease
-affects initiation, voluntary movements, sleep disturbances, labial emotions
Huntington's disease
-genetic, progressive
-dementia
-chorea: quick, jerky, purposeless, involuntary movements
-dysphagia
-explosive speech
Creutzfeldt-Jakob disease
-viral infection, transmissible
-causes cell destruction in cerebral cortex
-rapid onset, involuntary movements
pseudodementia
-reversible cognitive impairments seen in depression
-suspected when onset is abrupt, clinical course rapid, and client complains of cognitive failures
Cholinesterase Inhibitors
-treat DAT symptoms
-delaying destruction of ACh by acetylcholinesterase
-slows onset of decline, but will not alter the course
Donepezil and Tacrine are?
cholinesterase inhibitors
NMDA antagonist
-indicated for advanced DAT & has been shown to slow pace of deterioration
-blocks excess amts of glutamate that can damage nerve cells
-may help maintain patient function for a few months longer
Memantine is a?
N-methyl -D-aspartate
amyloid beta protein precursor (soluble) (sBPP)
-may be measured for diagnosing dementia
-decrease of sBPP in CSF supports diagnosis because amyloid tends to deposit in brain and is not circulating CSF
lab tests to rule out other treatable causes of dementia/delirium
CBC, serum electrolytes, BUN, glucose, Vitamin B12, folate, thyroid & liver function,test for syphilis, toxicity screening (heavy metal), alcohol screening
STOP acronym for caregivers to prevent burnout and fatigue
Slow down
Think about whats happening
Options
Plan to have time to unwind