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41 Cards in this Set
- Front
- Back
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Delirium & cognition
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-reduced ability to differentiate sensory information from hallucinations, dreams, illusions, imagery
-fragmented & disorganized thinking - unable to reason, judge, abstract, solve problems - unable to form memories or store & retrieve info |
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delirium & attention/wakefulness
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-difficulty with: alertness, selectiveness, directiveness
-wakefulness reduced during day, leading to naps & drowsiness -sleeplessness, agitation at night |
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delirium & psychomotor behavior
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-alternates between hyperactive & hypoactive
-slurred & disjointed sleep, aimless vocalizations & repetitions -groping/picking at bedclothes, sudden movements |
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delirium & emotional disturbances
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-fear, anxiety, irritability, anger, euphoria, apathy
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delirium onset
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-acute, over hours or a few days
-especially common in children & after age 60 |
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delirium course
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-fluctuates
-symptoms usually worse at night |
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delirium duration
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may resolve in a few hours - few weeks
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delirium outcome
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recovery if underlying disease is corrected or self-limiting
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delirium etiologic factors
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-systemic infections
-metabolic disorders (hypoxia, hepatic or renal disease, hypoglycemia) -postoperative states -substance intoxication& withdrawal -head trauma |
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depression characteristics
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-dysphoric mood ranging from mild, transient feelings of sadness to a severe sense of helplessness & hopelessness
-loss of interest in usual activities -appetite & sleep disturbances -difficulty concentrating/thinking -decreased energy -feelings of anxiety, irritability, fear, brooding |
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depression onset
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-able to date with some precision
-variable; symptoms usually develop over period of days to weeks but may be sudden |
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depression course
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-often not recognized or misdiagnosed in older adults
-can be masked by symptoms of dementia (disorientation, memory loss, apathy, inattentiveness) |
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depression duration
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-self limiting
-median time period is 8 months; may last up to 2 years |
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depression outcome
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-can be successfully treated
-spontaneous recovery is expected -severe may end in suicide |
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depression etiologic factors
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-situational: bereavement, loss of health, major catastrophic event, trauma
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dementia characteristics
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-memory impairment
-aphasia,apraxia,agnosia -decline in occupational/social functioning -spatial disorientation, poor judgment -violence, suicidal behavior -slurred speech, anxiety, mood & sleep disturbances -delusions, hallucinations |
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dementia onset
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-depends on underlying etiology
-may be sudden (head trauma) or slow -progress is relentless over several years |
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dementia course
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-depends on underlying etiology
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dementia duration
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-may progress to death over several years
-may be slowed |
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dementia outcome
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-generally irreversible
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aphasia
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loss of language ability
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agnosia
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-loss of sensory ability to recognize objects
-initially, can't recognize everyday objects. in later stages, can't recognize loved ones or body parts |
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apraxia
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-loss of purposeful movement without loss of muscle power
-ability to conceptualize/perform motor tasks deteriorates |
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see box 14-1, Kneisl p. 303 for behavioral changes of DAT
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right now
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early stages of DAT mini mental score
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>18
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moderate DAT mini mental score
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12-18
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severe DAT mini mental score
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<12
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Dementia with Lewy Bodies (DLB) pathophys
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-lewy bodies are abnormal concentrations of protein that develop inside nerve cells
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DLB manifestations
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-parkinsonian features
-persistent or recurrent visual hallucinations -fluctuating cognition |
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Vascular dementia
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-rapid onset
-one-sided weakness, emotional outbursts, stepwise rather than progressive decline in intellectual functioning -history of HTN, diabetes, cardio disease |
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Parkinson's disease
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-affects initiation, voluntary movements, sleep disturbances, labial emotions
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Huntington's disease
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-genetic, progressive
-dementia -chorea: quick, jerky, purposeless, involuntary movements -dysphagia -explosive speech |
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Creutzfeldt-Jakob disease
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-viral infection, transmissible
-causes cell destruction in cerebral cortex -rapid onset, involuntary movements |
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pseudodementia
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-reversible cognitive impairments seen in depression
-suspected when onset is abrupt, clinical course rapid, and client complains of cognitive failures |
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Cholinesterase Inhibitors
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-treat DAT symptoms
-delaying destruction of ACh by acetylcholinesterase -slows onset of decline, but will not alter the course |
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Donepezil and Tacrine are?
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cholinesterase inhibitors
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NMDA antagonist
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-indicated for advanced DAT & has been shown to slow pace of deterioration
-blocks excess amts of glutamate that can damage nerve cells -may help maintain patient function for a few months longer |
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Memantine is a?
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N-methyl -D-aspartate
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amyloid beta protein precursor (soluble) (sBPP)
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-may be measured for diagnosing dementia
-decrease of sBPP in CSF supports diagnosis because amyloid tends to deposit in brain and is not circulating CSF |
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lab tests to rule out other treatable causes of dementia/delirium
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CBC, serum electrolytes, BUN, glucose, Vitamin B12, folate, thyroid & liver function,test for syphilis, toxicity screening (heavy metal), alcohol screening
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STOP acronym for caregivers to prevent burnout and fatigue
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Slow down
Think about whats happening Options Plan to have time to unwind |