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28 Cards in this Set
- Front
- Back
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Mesoderm that gives rise to urogenital system
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Intermediate
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Components of urogenital ridge
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Gonadal ridge and nephrogenic cord
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Pronephros
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Begins Week 4 by capillaries invading nephrogenic cord; ends week 4
Forms excretory units from capillaries (from developing aorta) + tubules Goes away |
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Mesonephros system
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Begins Week 4
Two components: Renal corpuscle and mesonephric duct Renal corpuscle (blood filtering unit): glomerulus and bowman's capsule Mesonephric ducts: final pathway for excretory tubules |
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Metanephros system
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Begin Week 5; functional by Week 10
2 components it grows from: ureteric bud and metanephric blastema |
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Another name for mesonephric duct
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Wollfian duct
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Timing of Metanephros development and when they are functional
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Week 5 and Week 10
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Ureteric bud
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Outgrowth of mesonephric duct
Forms collecting system of kidney Ureter-->Renal Pelvis-->Major calyx-->Minor calyx-->Collecting tubules |
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Ureteric bud and metanephric blastema relationship?
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Ureteric bud penetrates metanephric blastema
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Adult derivatives of ureteric bud
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Ureter, renal pelvis, major calyx, minor calyx, collecting tubules
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Adult derivatives of metanephric blastema
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Metablastemic tubules: distal convoluted tubule, loop of Henle, proximal convoluted tubule, Bowman's capsule
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Congenital abnormalities of kidney
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Ectopic and horseshoe kidney
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Blood flow changes to kidney?
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Metanephros receives blood supply at progressively higher levels until definitive renal arteries develop at L2. Arteries formed during ascent may persist as supernumerary arteries
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Cause of renal agenesis?
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Oligohydraminos
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Urine/Amniotic fluid relationship
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Urine is secreted into amniotic fluid and ingested
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Germ layers that give rise to the bladder
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Surrounded by splanchnic mesoderm, lined with endoderm
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Urorectal septum makes what compartments from cloaca?
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Urogenital sinus and anal canal
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Subdivisions of urogenital sinus
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Upper, Pelvic, Phallic
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Upper subdivision of urogenital sinus
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Contributes to bladder and is continuous with allantois
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Pelvic subdivision of urogenital sinus
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Prostatic and membranous urethra
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Phallic subdivision of urogenital sinus
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Related to growth of genital ridge and differs between males and females
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Urachus
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Canal that drains fetal bladder; Fibrous remnant of allantois; median umbilical ligament
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Mesonephric duct contribution to bladder
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Ends absorbed into dorsal wall; becomes the trigone
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Fate of mesonephric ducts in males and females
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Males: develops into epididymis, ductus deferens, seminal vesicle
Females: Regresses |
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Exstrophy of bladder
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Maldevelopment of the lower abdominal wall, leading to a rupture which causes the trigone to be seen and urine drips from breach; exposure of posterior mucosal wall of bladder
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Development of suprarenal cortex
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From mesoderm between root of mesentery and urogenital ridge; present at birth, regresses, and replaced by second local mesoderm proliferation to form definitive cortex
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Development of suprarenal medulla
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Neural crest cells migrate and penetrate medial aspect of fetal cortex;
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Chromaffin cells
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Neural crest cells will differentiate into epinephrine containing cells that stain with chromium salts
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