- Shuffle
Toggle OnToggle Off
- Alphabetize
Toggle OnToggle Off
- Front First
Toggle OnToggle Off
- Both Sides
Toggle OnToggle Off
Front
How to study your flashcards.
Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key
Up/Down arrow keys: Flip the card between the front and back.down keyup key
H key: Show hint (3rd side).h key
PLAY BUTTON
PLAY BUTTON
10 Cards in this Set
- Front
- Back
|
Which complement components recruit inflammatory cells
|
C3a, C4a, C5a
|
|
Which complement components opsonize pathogens
|
C3b
|
|
Which complement components clear immune complexes
|
C3b
|
|
Which complement components kill pathogens
|
C5b, C6, C7, C8, C9
(aka the Membrane Attack Complex "MAC") |
|
How is MAC activated in
1. Classic pathway 2. Alternative pathway |
1. IgG and/or IgM (GM makes classic cars)
2. Endotoxins on the surface of microbes |
|
Which complement components are involved in anaphylaxis
|
C3a, C5a
|
|
Which complement components are involved in neutrophil chemotaxis
|
C5a
|
|
C3 deficiency means...
|
1. severe recurrent pyogenic sinus/respiratory infections
2. Inc. succeptibility to type III hypersensitivity (Ab-Ag complexes) |
|
What keeps complement from attacking self cells?
|
Decay-accelerating factor (DAF) and C1 esterase inhibitor
Note: DAF deficiency leads to paroxysmal nocturnal dyspnea b/c of complement attack on RBCs |
|
MAC is primary useful against
|
Gram - bacteria (especially Neisseria)
|
