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7 Cards in this Set
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- Back
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What are the dopamine agonists used to Tx Parkinson?
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1. Ergot = Bromocriptine & Pergolide
2. Pramipexole & Ropinirole |
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What adjunts are used in Parkinson tx?
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1) DDI's (DA Decarboxylase Inhibitors) = Carbidopa
2) COMT-I = "Capones" e.g. Entacapone & Tolcapone 3) MAO-B-I's = Selegiline |
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Which ACh-related drug is used for Parkinsonian symptoms?
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Benztropine = MAch antagonist
Helps w/ Tremor & Rigidity (doesn't help w/ slowed movement = bradykinesia) |
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What neurotransmitter is decreased in Alzheimer's Dz & in what regions of the brain?
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ACh
1) Nucleus Basalis of Mynert 2) Hippocampus |
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Which TB treatment is most effective against intracellular MTB (that has been phagocytized by macrophages)?
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Pyrazinamide = activated in the acidic phagolysosomes
inhibits fatty acid synthase I therefore blocking mycolic acid synthesis |
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Which TB treatment is most effective against intracellular MTB (that has been phagocytized by macrophages)?
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Pyrazinamide = activated in the acidic phagolysosomes
inhibits fatty acid synthase I therefore blocking mycolic acid synthesis |
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What are the glycogen storage diseases?
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I = Von Gierke's = G6Phosphatase (can't gluconeogenesis)
II = PomPe's = α1,4 glucosidase III = Cori's = α1,6 glucosidase (debranching) V = McArdle's = Glycogen phosphorylase |
