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17 Cards in this Set
- Front
- Back
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_______________ swelling occurs in the first 15 minutes following ischemia
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_Low amplitude_ swelling occurs in the first 15 minutes following ischemia
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pH drops in a cell following ischemia due to _________ build up
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pH drops in a cell following ischemia due to _lactic acid_ build up
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The loss of of _____________
means the e- transport chain is now broken and only partial reduction of oxygen can now occur leading to free radical production |
The loss of of _cytochrome c_
means the e- transport chain is now broken and only partial reduction of oxygen can now occur leading to free radical production |
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MPT stands for -
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Mitochondrial Permeability Transition
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Influx of ________ draws water into the cell, while ___________ entering the cell leads to activation of membrane lipases
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Influx of __Na+___ draws water into the cell, while _Ca++___ entering the cell leads to activation of membrane lipases
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Necrosis may be identified by light microscopy immediatel following the MPT - T/F
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F necrosis may only be identified much later
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The most damaging free radical is the
a Hydroxyl radical OH b Superoxide anion O2 |
a Hydroxyl radical
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The most common free radical is the
a Hydroxyl radical OH b Superoxide anion O2 |
b superoxide anion
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Selenium is neccesary for which enzyme to function
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Glutathione peroxidase
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Two important inducers of MPT are
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Free radicals
Calcium |
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DUring apoptosis cytochrome c release from the electron chain is caused by what small protein
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APAF-1 (Apoptosis Activating Factor - 1)
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APAF-1/cytochrome c activate which caspase
A) Caspase 8 B) Caspase 9 C) Caspase 10 |
B)Caspase 9
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Cytotoxic T cells activate which caspase
A) Caspase 8 B) Caspase 9 C) Caspase 10 |
C) Caspase 10
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Receptor mediated apoptosis activates which caspase
A) Caspase 8 B) Caspase 9 C) Caspase 10 |
A) Caspase 8
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Which caspase is responsible for most morphological changes in apoptosis
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Caspase 3
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______________ degradation allows the cell to "round up"
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__Cytoskeletal_____ degradation allows the cell to "round up"
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The two basic mechanisms by which
apoptotic necrosis can be triggered are |
Induction
Release phenomenon |
