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8 Cards in this Set
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- Back
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What is the concept of clinical latency
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Though a patient may appear well, have a stable CD4 count and partially controlled viral load, the virus is actively destroying CD4 cells in the lymphatics
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The opportunistic infections causing morbidity and mortality in HIV patients are often the result of what
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Reactivation of latent infections. Appropriate timing of the institution of prophylactic therapy can prolong quality and quantity of life
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When is the HIV patient at risk for Pneumocystis pneumonia
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CD4<200
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When is the HIV patient at risk for toxoplasmosis
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CD4<100
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When is the HIV patient at risk for Cytomegalovirus and Mycobacterium avium complex
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CD4<50
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When is primary prophylaxis used for the HIV patient
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Life threatening infection, to prevent reactivation. Examples include PCP, MAC, Toxoplasmosis, TB
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How often should CD4 count and HIV viral load be monitored
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Every 3-6 months. Helps determine when to start treatment, and assess response to antiretrovirals
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What are the five classes of HIV drugs
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Nucleoside (analogs) reverse transcriptase inhibitors (NRTI)
Nucleotide reverse transcriptase inhibitors Non nucleoside reverse transcriptase inhibitors (NNRTI) Protease inhibitors (PI) Fusion inhibitors |
