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DNA viral genomes
**all are dsDNA except PARVO (1 Par hole in golf)
RNA viral genomes
all are ssRNA except REO (colti and rota)
= "repeato virus"
Positive-stranded ssRNA
PICk a RETRO FLAVor of THCC

Picorna
Retro
Flavi
Toga
Hepe
Calici
Corona

*these purified nucleic acids are infectious (= mRNA)
Naked viral genome infectivity
the following purified nucleic acids are infectious:
dsDNA (minus pox and HBV)
+ strand ssRNA

Naked nucleic acids of - strand ssRNA and dsRNA are NOT infectious; require enzymes contained in the complete virion
Haploid virus
only retro: 2 identical ssRNA (diploid)
Viral replication
DNA: in NUCLEUS (except pox)
RNA: in CYTOPLASM (except influenza and retro

the exceptions: flu, HIV, pox
Viral envelopes
Naked CPR and PAPP smear
Calici
Picorna
Reo
Parvo
Adeno
Papilloma
Polyoma

*enveloped viruses acquire their envelopes from plasma membrane when they exit cell;
Acquires envelopes from nuclear membrane
herpesviruses
non-linear DNA
Papilloma and polyoma (circular, supercoiled)
hepadna (circular, incomplete)
non-icosahedral DNA
Pox
DNA virus that does NOT replicates in nucleus
Pox:
carries own DNA-dependent RNA polymerase
Pox virus
dsDNA virus
linear
complex
largest DNA virus
does NOT replicate in nucleus bc carries own DNA-dependent RNA polymerase
DNA Viruses
HHAPPPPy viruses:
Herpes, HepB, PaPaPoPo (not paramyxo, which follows orthomyxo)

Hepadna
Herpes
Adeno
Pox
Parvo
Papilloma
Polyoma
Characteristics of DNA viruses
DNA

Double stranded
Nucleus replication
Acosahedral
LINEAR
Negative-stranded RNA viruses
Must transcribe neg strand to positive
*virion brings its own RNA-dependent RNA polymerase

BARF OP negative strands
Bunya
Arena
Rhabdo
Filo

Orthomyxo
Paramyxo
Segmented viruses
all are RNA:
BOAR:
Bunya
Ortho
Arena
Reo

Ortho: 8 segments of neg-stranded RNA; undergo high-freq recombination via reassortment, causing antigenic shifts --> worldwide pandemics
Arboviruses
Transmitted By Fleas (mosquitoes, ticks)

Toga
Bunya
Flavi