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7 Cards in this Set
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- Back
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Neutrophils
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Polymorphonuclear granulocytes
Most numerous WBC Primarily phagocytosis. Mature phagocyte when released from bone marrow |
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Basophils
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Fewest WBC
Mobile mast cells—continues inflammatory response Secretes heparin, histamine, serotonin, kinins, leukotriens, & platelet activating factor Potentiates other vasoactive substances & inflammatory mediators Increase leukocyte adherence to & permeability through capillary wall Induces blood clotting in damaged vessels |
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Eosinophil
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Intermediate in #
Responsible for combating infection and parasites Associated with allergy and asthma |
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Macrophages are found here...
(Reticuloendothelial system) |
Mobile cells
Skin and subcutaneous tissues (histiocytes) Lymph nodes Lung alveoli Liver sinusoids (Kupffer Cells) Spleen & Bone marrow |
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Rasburicase (Elitek)
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Recombinant form of urate oxidase
Inhibits uric acid to prevent kidney damage in Leukocytosis |
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Allopurinol (Aloprim, Zyloprim)
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Inhibits xanthine oxidase, the enzyme that synthesizes uric acid to prevent kidney damage in Leukocytosis
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Granulocyte-macrophage colony-stimulating factor (GM-CSF)—Leukine (sargramostim)
Granulocyte colony-stimulating factor (G-CSF) analog—Filgrastim |
Induce proliferation of stem cells to promote more WBC
Enhance activity of leukocytes Fever, chills, bone / joint pain |
