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11 Cards in this Set
- Front
- Back
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Interleukin 1(IL-1)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. innate immunity
2. monocytes, macrophages, endothelial c., epithelial c. 3. vasculature(inflammation), hypothalamus(fever), liver(acute phase proteins) |
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Tumor necrosis factor-α(TNF-α)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. innate immunity
2. macrophages 3. vasculature(inflammation), liver(acute phase proteins), loss of body muscle/fat, neutrophil activation, cell apoptosis |
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Interleukin 12(IL-12)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. innate immunity
2. macrophages, dendritic c. 3. NK cells 4. influences adaptive immunity (increases B-cells and their secretions) |
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Interleukin 6(IL-6)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. innate immunity
2. macrophages, endothelial c. 3. liver(acute phase proteins), influences adaptive immunity (increases B-cells and their secretions) |
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Interferon α(INF-α)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. innate immunity
2. macrophages 4. activates NK c., induces antiviral state, increases MHC I |
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Interferon β(INF-β)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. innate immunity
2. fibroblasts 3. activates NK c., induces antiviral state, increases MHC I |
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Interleukin 2(IL-2)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. adaptive immunity
2. T cells 3. increases T-cells, B-cells, & NK cells, activates NK c. |
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Interleukin 4(IL-4)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. adaptive immunity
2. Th2 cells, mast cells 3. TH2 cell differentiation, isotope switch to IgE |
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Interleukin 5(IL-5)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. adaptive immunity
2. Th2 cells 3. Eosinophil activation and generation |
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Transforming growth factor β(TGF-β)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. adaptive immunity
2. T cells, macrophages, other cell types 3. Inhibits all T-cell activity, B-cell prolif., inhibits macrophages, isotope switch to IgA |
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Interferon γ(INF-γ)
1. Type of Immunity 2. Secreted by... 3. Target 4. Effect |
1. adaptive immunity
2. Th1, CD8+, NK 3. activates macrophages, increases MHC I, MHC II, and antigen presentation |
