These factors include:
• Pharmaceuticals
• Nutriceuticals
• Diet
• Physical and cognitive activity
Pharmaceuticals
A number of pharmaceutical agents are under investigation for potential to prevent AD. Of these, the leading candidates are:
• Non-steroidal anti-inflammatory drugs (NSAIDs)
NSAIDs are cyclooxygenase inhibitors that are usually used for pain relief and may serve in neuroprotection by reducing …show more content…
In addition to that, a large epidemiological study found that estrogen given early in menopause reduced Alzheimer’s risk. Other hormones such as testosterone has been linked to the existence of Alzheimer’s disease as it has shown neuroprotective effects on animals in certain studies. (Hogervorst, Bandelow, & Moffat,2005).
• Antihypertensive drugs
High blood pressure, has been linked with the increase in risk of developing Alzheimer’s disease (Kivipelto et al., 2001; Skoog & Gustafson,2006). Therefore, studies are trying to prove whether the link is to be taken into consideration or not.
Other agents such vaccines, secretase inhibitors, and anti--sheet conformational agents are being developed specifically as a prevention of Alzheimer’s.
Nutriceuticals
• Vitamins E and C
Vitamin E and Vitamin C are 2 of the most common antioxidants. The pathological events of Alzheimer’s disease are thought to be linked with the oxidative mechanisms (Behl,1999). Intake of antioxidants have been shown to decrease oxidative DNA damage. Studies have shown reduction in the risk of Alzheimer’s disease upon intake of antioxidant supplements (Engelhard et al., 2002; Morris et al.,