Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
89 Cards in this Set
- Front
- Back
|
a drug which alleviates pain: ?
|
Analgesic
|
|
|
a drug which abolishes/blunts memory or events: ?
|
Amnestic
|
|
|
agent which induces sleep: ?
|
Hypnotic
|
|
|
the onset of the anesthetic: ?
|
Induction
|
|
|
the termination of an anesthetic, when the patient "wakes up": ?
|
Emergence
|
|
|
Nitrous Oxide: drug class
|
inhaled anasthetic
|
|
|
Nitrous Oxide: hypoxia?
|
no
|
|
|
Nitrous Oxide: rate of induction?
|
slow
|
|
|
Nitrous Oxide: respiratory depression
|
no
|
|
|
Nitrous Oxide: cardiac depression
|
no
|
|
|
Ether: drug class
|
inhaled anasthetic
|
|
|
Ether: hypoxia?
|
yes
|
|
|
Ether: rate of induction?
|
fast
|
|
|
Ether: respiratory depression
|
yes
|
|
|
Ether: cardiac depression
|
yes
|
|
|
Chloroform: : drug class
|
inhaled anasthetic
|
|
|
Chloroform: : cardiac depression
|
yes
|
|
|
Chloroform: : hepatic toxicity
|
yes
|
|
|
The Fluorinated Anesthetics: 3 from class
|
halothane, isoflurane, sevoflurane
|
|
|
Halothane : drug class
|
inhaled anasthetic
|
|
|
Halothane : chemistry
|
alkane
|
|
|
Halothane : hepatic toxicity
|
just a lil bit
|
|
|
Halothane : flammable
|
no
|
|
|
Isoflurane, : drug class
|
inhaled anasthetic
|
|
|
Isoflurane, : chemistry
|
ether
|
|
|
Isoflurane, : emergence rate
|
slow
|
|
|
Isoflurane, : cardiovascular efx
|
just a lil myocardial depresion; decreased systemic vascular resistance
|
|
|
Isoflurane, : respiratory efx
|
irritates airways; depression
|
|
|
Isoflurane, : hepatic efx
|
no hepatitis
|
|
|
Sevoflurane: : drug class
|
inhaled anasthetic
|
|
|
Sevoflurane: : chemistry
|
ether
|
|
|
Sevoflurane: : rate of induction?
|
fast
|
|
|
Sevoflurane: : emergence rate
|
fast
|
|
|
Sevoflurane: : blood solubility
|
low
|
|
|
MAC (minimum alveolar concentration): importance to anesthesia
|
expression of potency; concentration necessary at 1 atm that prevents movement in 50% subjects from pain
|
|
|
MAC-BAR: importance to anesthesia
|
concentration necessary to Block Adrenergic Response
|
|
|
Nitrous Oxide: blood solubility
|
stupid low
|
|
|
Nitrous Oxide: odor
|
none
|
|
|
Nitrous Oxide: cardiovascular efx
|
minimal depression; increased pulmonary artery pressure
|
|
|
Nitrous Oxide: respiratory efx
|
minimal depression
|
|
|
Nitrous Oxide: CNS circ efx
|
increased cerebral blood flow
|
|
|
Nitrous Oxide: hematopoietic sx
|
megaloblastic anemia is possible (supression of methionine sythetase)
|
|
|
Halothane : flammable
|
no
|
|
|
Halothane : blood solubility
|
moderate
|
|
|
Halothane : odor
|
sweet
|
|
|
Halothane : cardiovascular efx
|
slows heart rate, potentiates epinephrine induced arrythmias, myocardial depression
|
|
|
Halothane : respiratory efx
|
depression
|
|
|
Halothane : CNS circ efx
|
increased cerebral blood flow; decreased cerebral metabolism
|
|
|
Halothane : musculoskeletal
|
promotes relaxation; esp uterine
|
|
|
Halothane : hepatic efx
|
halothane hepatiis; 1:222K anesthetics
|
|
|
Halothane : renal efx
|
decreased GFR and renal flow
|
|
|
Malignant Hyperthermia: ?
|
potentially lethal condition associated with inhaled N2O and succinylcholine
|
|
|
Malignant Hyperthermia: tx
|
dantrolene (blocks Ca into muscles)
|
|
|
ryanodine receptor : ?
|
sarcoplasmic reticulul Ca channel; linked to malignant hyperthermia (anasthesia)
|
|
|
Barbituates: Cytochrome metabolism
|
P450
|
|
|
Barbituates: counterindx
|
porphyria
|
|
|
Barbituates: respiratory depression
|
yup
|
|
|
Barbituates: cardiac depression
|
yup (preserved baroreceptor reflex)
|
|
|
Pentobarbital : Cytochrome metabolism
|
P450
|
|
|
Pentobarbital : drug class
|
barbituate
|
|
|
Pentobarbital : counterindx
|
porphyria
|
|
|
Pentobarbital : respiratory depression
|
yup
|
|
|
Pentobarbital : cardiac depression
|
yup (preserved baroreceptor reflex)
|
|
|
Pentobarbital : elimination half life
|
12 hours
|
|
|
Pentobarbital : histamine release?
|
yes
|
|
|
Methohexital : drug class
|
barbituate
|
|
|
Methohexital : counterindx
|
porphyria
|
|
|
Methohexital : elimination half life
|
4 hours
|
|
|
Methohexital : histamine release?
|
no
|
|
|
Midazolam : Cytochrome metabolism
|
CYP 3A4
|
|
|
Midazolam : drug class
|
benzodiazapine
|
|
|
Midazolam : active metabolites
|
yes
|
|
|
Midazolam : interax
|
competes at CYP 3A4 w/ erythromn; -anil's
|
|
|
Diazepam: drug class
|
benzodiazapine
|
|
|
Diazepam: active metabolites
|
yes
|
|
|
Lorazepam: drug class
|
benzodiazapine
|
|
|
Lorazepam: active metabolites
|
no
|
|
|
Ketamine:: drug class
|
phencyclidines
|
|
|
Ketamine:: mechanism
|
NMDA receptor antagonist
|
|
|
Ketamine:: hepatic metabolism
|
yes
|
|
|
Ketamine:: intramuscular ok?
|
yup
|
|
|
Ketamine:: clinical use
|
battlefield; no resp depression; use when need spontaneous ventilation
|
|
|
Etomidate : chemistry
|
imidazole derivative
|
|
|
Etomidate : positive aspects
|
more rapid awakening than barbitutes; cardiovascular stability
|
|
|
Etomidate : drawbacks
|
nausea; decreased seizure threshold; adrenal supression; myoclonic movements
|
|
|
Etomidate : eliminatino route
|
hepatic
|
|
|
Etomidate : clinical use
|
when hemodynamic stability important
|
|
|
Propofol : hepatic metabolism
|
oh yeah
|
|
|
Propofol : clinical use
|
anesthesia for breif procedures
|
