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virulence factor of staph aureus - binds Fc-IgG, inhibiting complement fixation and phagocytosis
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protein A
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superantigen that binds to MHC II and TCR, resulting in polyclonal T cell activation
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TSST - (staph aureus)
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what makes coagulase?
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staph aureus
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antibody to what enhances host defenses against strep pyogenes?
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M protein
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group A beta-hemolytic strep?
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strep pyogenes
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what detects recent strep pyogenes infections?
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ASO titer
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associated with rusty sputum, sepsis in sickle cell, and splenectomy?
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strep pneumo
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most common cause of meningitis, otitis, pneumonia, sinusitis?
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strep pneumo
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what gives immunity to strep pneumo?
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IgG antibodies to surface acidic polysaccharide
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causes pneumonia, meningitis, and sepsis mainly in babies
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group B strep (agalactiae) - beta hemolytic, bacitracin resistant
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what is Lancefield grouping based on?
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differences in the C carbohydrate on the bacterial cell wall
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what can grow in 6.5% NaCl
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enterococci
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enterococci can cause what?
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UTI, subacute endocarditis, biliary tract infections
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bacteria related to colon cancer?
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strep bovis
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type of strep viridans that can cause subacute bacterial endocarditis?
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strep sanguis
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what does C. perfringens produce?
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alpha toxin
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gram-positive rods with metachromatic granules?
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corynebacterium diphtheriae
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woolsorter's disease?
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bacillus anthracis
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inhalation of anthrax spores?
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flulike symptoms that rapidly progress to fever, pulmonary hemorrhage, and shock
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gram-positive anaerobe that causes oral/facial abscesses that may drain through sinus tracks in skin
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actinomyces
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gram positive, weakly-acid fast aerobe that causes pulmonary infection in immunocomprimised patients
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nocardia asteroides
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sulfur granules
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actinomyces
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gram-positive rods forming long branching filaments resembling fungi
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actinomyces & nocardia
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most invasive disease of H. flu is caused by what capsular type?
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B
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treatment for H. flu meningitis?
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ceftriaxone
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treatment for neisseria gonorrhea?
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ceftriaxone - also z pack or doxycycline because 50% will also be infected with chlamydia
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why don't you want to culture if pt. has epiglottitis?
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manipulation cause laryngeal spasm
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members of enterobacter family (7)
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e. coli, salmonella, shigella, klebsiella, enterobacter, serratia, proteus
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what antigen is related to the virulence of enterobacter?
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K antigen
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all of these ferment glucose and are oxidase negative
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enterobacter
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these bacteria grow pink colonies on MacConkey's agar
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klebsiella, e. coli, enterobacter (KEE), citrobacter
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salmonella or shigella: motile and can disseminate hematogenously?
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salmonella
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salmonella or shigella: which is more virulent?
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shigella
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salmonella or shigella: symptoms may be prolonged with antibiotic treatments
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salmonella
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salmonella or shigella: animal reservoir
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salmonella
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this is usually transmitted from pet feces, contaminated milk, or pork; outbreaks common in daycare centers
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yersinia enterocolitica
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this can mimic Crohn's or appendicitis & can disseminate to produce lymphadenitis
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yersinia enterocolitica
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arthritis can develop with yersinia infection in patients with what?
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HLA-B27
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vibrio parahaemolyticus and v. vulnificus
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contaminated seafood
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reheated rice
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B. cereus
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meats, mayonase, custard
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s. aureus
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reheated meat dishes
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c. perfringens
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undercooked meat
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e. coli 0157:H7
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poultry, meat, eggs
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salmonella
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bloody diarrhea; comma or S-shaped organisms
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campylobacter
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is campylobacter motile?
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yes
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e. coli producing shiga-like toxin; can cause HUS
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enterohemorrhagic
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day-care outbreaks, pseudoappendicitis
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yersinia
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protazoan causing bloody diarrhea
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entamoeba histolytica
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protaozoa causing watery diarrhea
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giardia, cryptosporidium (in immunocompromised)
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