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USMLE Microbiology

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Title: USMLE Microbiology
Description: USMLE Microbiology
Number of Cards: 258
Author: Matthew J Swenson
Created: 2006-12-03
Tags: (with-viruses) gen microbiology recall step1 swenson usmle usmle_microbiology_258_cards
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Question Answer Note/Hint
What does Candida albicans do that distinguishes it from other fungi? It forms a germinal tube at 37°C.
What protozoal parasite results in dysentery with blood and pus in the stool, is transmitted via fecal-oral route, is diagnosed by cysts or trophozoites in the stool, and forms liver abscesses and inverted flask-shaped lesions in the large intestine? Entamoeba histolytica (treat with metronidazole)
What is the most likely causative organism for a patient with folliculitis after spending time in a hot tub? Pseudomonas aeruginosa
What two viruses get their envelope not from budding but from coding? HIV and poxvirus
Which type of hepatitis can cause hepatocellular carcinoma? Hepatitis B
Gas gangrene is associated with which Clostridium species? Clostridium perfrigens
Which dimorphic fungus is found as hyphae with nondescript conidia in rotting wood in the Upper Great Lakes, Ohio, Mississippi, eastern seaboard of the United States, and southern Canada? Blastomyces dermatitidis
Which parasitic organism, when it crosses the placenta, results in intracerebral calcifications, chorioretinitis, microcephaly, hydrocephaly, and convulsions? Toxoplasma gondii
What staphylococcal species is positive for Beta-hemolysis and coagulase? Staphylococcus aureus
What vector is associated with malaria? Anopheles mosquito
What is the term for hyphae with constrictions at each septum that are commonly seen in Candida albicans? Pseudohyphae
Which cestode infection results in alveolar hydatid cyst disease? Echinococcus multilocularis
Which hepatitis virus is in the Flaviviridae family? Hepatitis C
What nonmotile gram-negative, non–lactose-fermenting facultative anaerobic rod uses the human colon as its only reservoir and is transmitted by fecal-oral spread? Shigella
What is the only Rickettsia that is stable in the environment? Coxiella burnetii
Regarding the viral growth curve, is the internal virus present before or after the eclipse period? After the eclipse period
What Ab is an indication of recurrent disease for hepatitis? HBc Ab
What small gram-positive, non–spore-forming rod is a facultative intracellular parasite that grows in the cold and is associated with unpasteurized milk products? Listeria monocytogenes
What is the only DNA virus that is not icosahedral? Poxvirus
Which organism causes trench mouth? Fusobacterium
True or false? All of the following are inactivated vaccines available in the United States: influenza, Vibrio cholera, hepatitis A, rabies, and adenovirus. False. Adenovirus vaccine is a live pathogenic virus in an enteric coated capsule. All of the others are inactivated vaccines.
Name the Plasmodium species based on the following information:
No persistent liver stage or relapse; blood smear shows multiple ring forms and crescent-shaped gametes; irregular febrile pattern; associated with cerebral malaria
Plasmodium falciparum
Name the Plasmodium species based on the following information:No persistent liver stage or relapse; blood smear shows rosette schizonts; 72-hour fever spike pattern Plasmodium malariae
Name the Plasmodium species based on the following information:Persistent hypnozoite liver stage with relapses; blood smear shows amoeboid trophozoites with oval, jagged infected RBCs; 48-hour fever spike pattern Plasmodium ovale
Name the Plasmodium species based on the following information:
Persistent hypnozoite liver stage with relapses; blood smear shows amoeboid trophozoites; 48-hour fever spike pattern; the most prevalent form worldwide
Plasmodium vivax
True or false? A positive PPD skin test indicates the patient has active pulmonary disease. False. The PPD tests exposure to TB.
What viral infection is known to cause intracerebral calcifications? CMV; Toxoplasma also causes intracerebral calcifications but it is a parasite.
What viruses are associated with cervical carcinoma? HPVs 16 and 18
What motile, gram-negative spiral bacillus with flagella is oxidase positive, urease positive, and associated with gastritis, peptic ulcer disease, and stomach cancer? Helicobacter pylori
What glycoprotein in the HIV virus is used for fusion? GP41
What Ag is needed to diagnose an infectious patient with hepatitis B? HBeAg
Which organism causes multiple infections by antigen switching? Borrelia recurrentis
What is the first Ag seen in an individual with hepatitis? HBsAg (incubation period)
With which DNA virus are Guarnieri bodies associated? Variola (smallpox)
What nematode is known as pinworms? What is the treatment? Enterobius vermicularis; the treatment is albendazole.
What protein allows Mycoplasma to attach to the respiratory epithelium? P1 protein
What organism is associated with the following types of diarrhea?
Day care–associated diarrhea in infants
Rotavirus
What organism is associated with the following types of diarrhea?
Watery diarrhea from beef, poultry, or gravies
Clostridium perfringens
What organism is associated with the following types of diarrhea?
Rice water stools
Vibrio cholera
What organism is associated with the following types of diarrhea?
Diarrhea associated with raw or undercooked shellfish
Vibrio parahaemolyticus
What organism is associated with the following types of diarrhea?
Bloody diarrhea associated with hamburger ingestion
Enterohemorhagic Escherichia coli
Which fungus is found worldwide on plants, is a cigar-shaped yeast in tissue form, and results in rose gardener's disease? Sporothrix schenckii
Which type of hepatitis is a picornavirus? Hepatitis A (infectious)
What gram-positive rod is distinguished by its tumbling motility? Listeria
What is the vector for Leishmania infections? The sandfly
What is the term of the viral growth period when no viruses can be found intracellularly? Eclipse period
What organism causes Q fever? Coxiella burnetii
What are the three naked RNA viruses? 1. Picornavirus
2. Calicivirus
3. Reovirus


(Remember PCR)
HIV's capsid, core nucleocapsid, and matrix proteins are products of what structural gene? gag gene
What facultative intracellular fungus is associated with hepatosplenomegaly? Histoplasma capsulatum infects the cells of the RES and can result in hepatosplenomegaly.
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