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23 Cards in this Set

  • Front
  • Back
gram positives how to differentiate?
STREPTOCOCCUS vs. STAPHYLOCOCCUS
gram-stain, Catalase differentialt
streptococci how to differentiate?
beta-hemolytic (complete lysis)
alpha-haemolytic (incomplete; green discoloration)
non-haemolytic
---
lancefield groups A, B, (C), D ... S
only 5 groups human pathogens
GROUP A BETA-HAEMOLYTIC STREPTOCOCCI
infections
skin infections (incl. necrotising fasciitis!)
scarlet fever
TSS
delayed antibody mediated:
rheumatic fever
glomerulonephritis
GROUP B STREPTOCOCCI
infections
neonatal meningitis
when treated, also cover:
E.COLI
LISTERIA
non lancefield
VIRIDANS GROUP ALPHA HAEMOLYTIC STREPTOCOCCI
infections
dental infections
abscess
endocarditis
GROUP D ALPHA HAEMOLYTIC STREPTOCOCCI (ENTEROCOCCI and NON-ENTEROCOCCI)
infections
ENTEROCOCCI (e. faecalis, e. faecium)
urinary infections
bilary infections
endocarditis
VRE!!!!
NON-ENTEROCOCCI
? colon Ca
non-lancefield
STREPTOCOCCUS PNEUMONIAE
(PNEUMOCOCCI)
infections
bacterial meningitis (most common organism in adults)
otitis media
pneumonia
risk factors for malignant melano ma
sun exposure
family history
atypical mole syndrome
giant congenital melanocytic naevic
lentigo maligna
what is lentigo maligna
melanoma in situ
dysplastic naevus cells grow slowly
appears as brown/black nodule with indefinite borders
patients >60 with sun exposure
change in color or bumps appearing signals transformation to lentigo maligna melanoma
HHT (haemorragic heredetary teleangiectasy) clinical features
autosomal dominant
nose and gastrointestinal tract most commonly affected
epistaxis and GI bleeding
iron deficiency anaemia
Treatment of tinea
1. localised tinea corporis/cruris (flexures)
topical TDS 1-2 weeks
2. more widespread or tinea manuum/pedis/capitis
itraconazole 100mg OD
terbinafine 250mg OD
1-2 months
3. tinea capitis in children
15-20mg/kg griseofulvin per day for 8 weeks
scabies clinical features
any age, social background
close contact
4-6 weeks after infection, hypersensitivity rash
extremely itchy, especially during night
usually face spared.
person with scabies and rash not disappearing
consider reaction to malathion
scabies management
* 5% malathion/permethrin
* treat all skin below neck incl. genitalia and under nails (infants: face and neck too)
* treat all close contacts, even if asymtomatic
* warn patient that rash still itchy for 4 weeks
* adjunct with emollient/mild steroid or crotamiton helpful.
lichen planus clinical features
unknown etiology
mauve (violaceus) plaque, flat topped shiny
white streaky areas (wickam striae)
itchy, mucousal involvement
in black people:
hypopigmentation around
disappears after 9-18 months
lichen planus treatment
potent topical steroid (+/- occlusion) or occasional oral steroid
if fails, PUVA, azathioprine, retinoids, topical tacrolimus.
pityriasis versicolor
clinical features
pityrosporum infection
young adults
trunc
asymptomatic
caucasians: reddish brown scaly macules
black: macular areas of hypopigmentation
pityriasis versicolor treatment
selenium sulpide shampoo or topical imidazole cream.
if fails, oral itraconazole
pigmentation takes months to recover
can reoccur
herpetic whitlow clinical features
recurrent "cellulitis" in young adults
vesiculo-papular rash on fingers
lymphangiits, lymphadenopathy and lymphoedema complications
oral hairy leucoplakia
associations
HIV, especially if smokers
bechet's, inflammatory bowel disease
CDLE - chronic discoid lupus erythematodes
clinical features
fixed erythematous, scaly atrophic plaque with teleangiectasia
sun exposed areas
UV light can aggravate
alopecia and mucous involvement in 25%
5% will develop SLE
ANA positive in 30%
CDLE treatment
sun screens
potent topical steroids
oral antimalarials (hydroxychloroquin)
bechet's disease
IS A VASCULITIS
recurrent aphtous oral ulcers (99%)
gastrointestinal ulcers (pain, malaena (50%)
genital ulcers
anterior/posterior uveitis
other: musculoskelettal/CNS, skin (EN)
venous AND arterial thromboses/thrombophlebitis, aneurism, stenoses (up to 40%)