memory B-cells begin to replicate and produce antibodies much efficiently, e.g. wild hepatitis A virus infection (Baxter, 2007; Portnoy, 2004). There are however, some exceptions e.g. malaria. Individuals develop only a partial immunity against Plasmodium falciparum even after multiple exposure to malaria. Individuals with this type of partial immunity may still be infected but do not display severe disease conditions. It is also important to note that level of risk of infection directly affects…
3. Why a malaria vaccine is required? When microorganism enter the body, the immune system fight these foreign antigens by production of T or B-lymphocytes that produces antibodies, which effectively neutralize foreign invaders. Human body take several days to produces antibodies, while microorganism attack and multiply in the body and produce serious illness before immune system can fit back, this is a reason behind the vaccine manufacturing and development (CDC, 20175; Sarkander et al., 2016;…
comparative molecular field analysis (CoMFA), and a comparative molecular similarity indices analysis (CoMSIA) studies on a series of benzo[b]thiophene-containing selective inhibitors of plasmodial NMT. Two QSAR models were constructed, one for Plasmodium falciparum NMT and another for Homo sapiens NMT, for each QSAR method. The predictive ability of all QSAR models was significant (r2 > 0.90 and q2 > 0.70). Comparing results of different enzymes, we achieved great understanding of…
Assessment Although the majority of people from India believe in Hinduism, not all of them believe in it. If a health care worker were to do an assessment on someone from India, it would be good to ask what their beliefs are and how important it is to them. This way the health care worker can be more familiar on the amount of care they need. One could ask if there is a group they attend and how important it is to them. This is a good way of getting the feel for the reasons they may make…
cell, red blood cell infected by Plasmodium falciparum, or red blood cell infected by Plasmodium vivax? Lowest? What are the implications for disease (i.e., what happens when the infected cells are stiff? Compliant?) The elastic modulus of the red blood cell affected by Plasmodium falciparum is considered to be the highest as it stiffness increases still it reaches the schizont stage of infection .While the lowest elastic modulus is for the cell affected by Plasmodium…
Retrospective diagnosis is examining the evidence/archives from ancient medicine or any other era and comparing that data to today’s era of medicine, or it can be to diagnose a patient from the past with today’s knowledge by using the documents and/or artifacts that may be relevant or pertain to the patient. Therefore, this paper is going to examine how retrospective diagnosis works, examples of retrospective diagnosis, it’s strengths and weaknesses, and why retrospective diagnosis is important…
There are many theories of how Alexander the Great died. It is still a mystery on how the magnificent ruler passed away, but scientists feel they have an idea of what could have caused his death. Alexander the Great was the king of Macedonia in 336 BC. He conquered most of the known world in his lifetime; astoundingly forming one of the ancient world’s largest empires, which spread from Greece to present day Turkey. Some may conclude to call him “one of history’s most successful commanders.” But…
Introduction The essay is aimed at looking at the extent to which the use of traditions, alternative medicine and cultural factors play a vital part on the successful implementation of global health programs (GHP) in Cameroon. “Traditional Medicine(TM)” according to (WHO, 2015) is attributed to knowledge, skills and practices established on theories, beliefs and experiences primitive people of various cultures use in maintaining good health, preventing health issues and treating physical and…
Cambodia: Epidemiology and Public Health Description and Health Profile Cambodia is a Southeast Asian country home to 14.5 million people, bordered by Thailand, Laos and Vietnam.1 After the communist Pol Pot regime and era of the Khmer Rouge came to an end in the 1970’s, the country has been slowly recovering from the Cambodian genocide and its ramifications.1 The last twenty years have seen relative stability in Cambodia, which has translated into significant improvements in population…
Sickle cell anaemia describes a hereditary autosomal recessive disorder that affects a protein found in red blood cells (erythrocytes) called haemoglobin. Erythrocytes contain about 280 million haemoglobin molecules that are composed of globulin protein and a heme molecule that binds to iron. Haemoglobin allows respiration of oxygen and exchange of carbon dioxide in blood, essential for all body systems. This disorder, determined at contraception, results in 100% of blood cells becoming sickle…