Solubility

Discussion For the first part of the experiment, a solubility test was conducted on all compounds. Because they were all ionic, every known compound naturally dissolved in water, and conducted electricity. As the next determining factor in the process to identify the unknown substance, the compounds were tested in acetone. As seen in table 2, only one compound, Ca(NO3)2 was found to be soluble in this solvent. Because the unknown solid was insoluble in acetone, Ca(NO3)2 was then eliminated as a…

shells, so that each could be individually massed and the percentage-by-mass could be determined. The best way to get the sand and shells by themselves is to get rid of the salt. Since salt is dissolvable in water, you use water solubility (Hallows, 2014). Water solubility is defined as a substance being able to completely dissolve in water (“Water Soluble”). So setting up the filtration and having salt completely gone was a physical change (Hallows, 2014). The next two components that are left…

Identification of Unknown Compounds 64A and 64B 64A, was a white powdery solid substance. 64B, was a clear colorless liquid that had the smell of alcohol. Solubility analysis is a method of identifying compounds based on how their behavior in other compounds. Solubility is the ability of a solvent to dissolve a solute. For a solvent to dissolve a solute, it has to be able to break the intramolecular forces of the solute. The intermolecular forces between the solvent and the solute have to be…

Wang et al. (2015) formulated a solid dispersion to improve the solubility and bioavailability of Ginkgo biloba extract (GE) through hot melt technology. The polymer studied were Kollidon® VA64/Kolliphor® RH40 (85:15) and the extrusion was carried out at 120-125⁰C with 100 RPM with 25% drug load. DSC and XRD studies confirmed the amorphous conversion of the GE and the dissolution carried in 250ml of 0.1N HCl showed that the dissolution of solid dispersion of GE was significantly improved (2-3…

a. The solubility of primary alcohols in water compared to that of alkanes. Explain the difference in terms of intermolecular forces. Solubility of alcohols in water Small alcohols are completely soluble in water; mixing the two in any proportion generates a single solution. However, solubility decreases as the length of the hydrocarbon chain in the alcohol increases. At four carbon atoms and beyond, the decrease in solubility is noticeable; a two-layered substance may appear in a test tube when…

The motivation behind this experiment was to gain insight behind the theory and practice of two laboratory techniques: solubility-dependent extraction, and recrystallization, in an effort to isolate and identify three compounds originally dissolved in a mixture. Extraction is used to isolate a specific compound. Recrystallization involves taking a crude compound and removing unwanted impurities so that a more accurate melting point can be taken, leading to a more precise identification of a…

innate protein particles or aggregates.However, there is a mechanistic difference between the two aspects. In the case of a pure solubility issue, i.e. a protein becomes insoluble in a certain solution (no changes in protein structure and integrity) and a solid phase is formed, a strong dilution of the system may lead to the dissolution of the protein. In such a circumstance, the term “protein associates” may more appropriately describe the formed protein solid .In this instance, protein…

Solubility studies The solubility of docetaxel in various vehicles selected as oil, surfactant and co-surfactant for formulation of L-SNEDDS was determined and presented in the Table 1. Among the tested vehicles, Capmul PG8 NF (>250 mg/mL), Capmul MCM C8 (>250 mg/mL) and Transcutol P (>200 mg/mL) had the highest drug solubilization capacity for docetaxel. Whereas, Captex and Gelucire 44/14 shown the least solubility of docetaxel in them. Based on the solubility results, Capmul PG8 NF…

Solubility property of ozone is dependent on several extrinsic factors such as temperature, pressure, composition of the medium, pH, gas flow rate, etc. Henry’s law says that the pressure of the gas exerts above the liquid is directly proportional to the solubility of the ozone (Bablon et al., 1991). De Smedt et al. (2001) revealed that solubility of ozone is dependent on pH, temperature and type of additives of the aqueous solution. Levanov et al. (2008) found that solubility of ozone decreased…

that can dissolve into a liquid with their solubility causing an increase in temperature. The solvent molecules of a liquid can break apart solute molecules (that are supposed to be bonded by intermolecular attractions) by the increase of kinetic energy. Whereas, kinetic energy increases with temperature and its vibrations causes the solute molecules to dissolve more easily. Kinetic energy is energy that a body possesses by virtue of being in motion. Solubility is the ability for a given…