Malignant cells with these functional properties have been designated as cancer stem cells (Jordan, et al. 2006). It is possible for cancer stem cells arise from regular stem cells through random mutations. However, studies indicate that cancer stem cells can also arise from mutated progenitor cells that possess replicative ability, but do not have the self-renewal capacity of stem cells (Jordan, et al. 2006). To become a cancer stem cell, a progenitor cell must acquire mutations that allows it to regain the property of self-renewal (Jordan, et al. 2006). Cancer stem cells can arise from different origins, but they share a common property of
Malignant cells with these functional properties have been designated as cancer stem cells (Jordan, et al. 2006). It is possible for cancer stem cells arise from regular stem cells through random mutations. However, studies indicate that cancer stem cells can also arise from mutated progenitor cells that possess replicative ability, but do not have the self-renewal capacity of stem cells (Jordan, et al. 2006). To become a cancer stem cell, a progenitor cell must acquire mutations that allows it to regain the property of self-renewal (Jordan, et al. 2006). Cancer stem cells can arise from different origins, but they share a common property of