There are several checkpoints the eukaryote cell cycle that controls the cells from proceeding from one to the next phase of the cell cycle. The point where the cells start to enter the cell cycle is at the G1 checkpoint, which is also known as the restriction checkpoint. At this point, the Retinoblastoma interacts with the E2F, which is the transcription factor to make cyclin E causes the E2F to be inhibited upon interaction. Cells with damaged DNA get arrested at the G1 checkpoint and is prevented from entering the S phase. The DNA damage has to be repaired before moving on to the next phase. DNA has to be replicated to pass the checkpoint in the S phase. Signals can cause the cells to be delayed in the
There are several checkpoints the eukaryote cell cycle that controls the cells from proceeding from one to the next phase of the cell cycle. The point where the cells start to enter the cell cycle is at the G1 checkpoint, which is also known as the restriction checkpoint. At this point, the Retinoblastoma interacts with the E2F, which is the transcription factor to make cyclin E causes the E2F to be inhibited upon interaction. Cells with damaged DNA get arrested at the G1 checkpoint and is prevented from entering the S phase. The DNA damage has to be repaired before moving on to the next phase. DNA has to be replicated to pass the checkpoint in the S phase. Signals can cause the cells to be delayed in the