The salts aggregated into a colloid state as small molecule, and with added urate they increase in size. Ammonium ions are the most prone to become flakes and leave the colloid suspension causing buildup of aggregates that obstruct the urinary tract. The article found that dietary purine helps to increase the amount of uric acid being excreted. These types of uroliths are not common in most mammals with the exception of Dalmatian dogs, humans, apes, and Eurasian otters because they lack uricase to convert uric acid into allantoin. Allantoin can pass through the kidneys without causing crystals unlike uric acid. In humans, the concentrations of uric acid are the cause of gout. (Ruff et al., 2007). The maned wolf is classified as an endangered species in Brazil. In this study, three of the four wolves that were observed died because of urolithiasis. Two of the male maned wolves were born in captivity and the other two were captive bred. The wolves that were studied had different signs varying in degrees that included abdominal distension, urinary tract infections, pain in the abdomen, incontinence, difficulty
The salts aggregated into a colloid state as small molecule, and with added urate they increase in size. Ammonium ions are the most prone to become flakes and leave the colloid suspension causing buildup of aggregates that obstruct the urinary tract. The article found that dietary purine helps to increase the amount of uric acid being excreted. These types of uroliths are not common in most mammals with the exception of Dalmatian dogs, humans, apes, and Eurasian otters because they lack uricase to convert uric acid into allantoin. Allantoin can pass through the kidneys without causing crystals unlike uric acid. In humans, the concentrations of uric acid are the cause of gout. (Ruff et al., 2007). The maned wolf is classified as an endangered species in Brazil. In this study, three of the four wolves that were observed died because of urolithiasis. Two of the male maned wolves were born in captivity and the other two were captive bred. The wolves that were studied had different signs varying in degrees that included abdominal distension, urinary tract infections, pain in the abdomen, incontinence, difficulty