Epidemiology and Mechanisms of the disease The Nephrogenic Diabetes Insipidus is firstly a rare disease to get or it can be inherited and the rate of getting it is 1 in 20 million which shows how rare this condition is. The cause is that the body has low levels of Arginine Vasopressin (AVP) and Antidiuretic hormone (ADH) which then cause the kidneys unable to concentrate the urine which is called polyuria which leads to excessive amount of urine being produced which leads to polydipsia. So when fluid levels intake is very low the ADH levels increases which make the kidney produce less urine and then when the fluid intake is very high the ADH decreases and ends up making the kidneys produce more urine. But they are many ways which you can be diagnosed with NDI such as being inherited with them which is mostly caused by genetic mutations (AQP2 gene) in the family genes and result in interference with the …show more content…
It must be packaged securely with a hazard sign to warn of potential danger to others. It only should be handled by people who what they are doing in a safe environment so it does it affect or harm anyone else. How to handle this a lab is firstly it should only be done or carried out by trained scientists or doctors who know what they are doing it, the lab should be secure so if something does happen the disease will stay in the lab and wont spread out and affect other. You should be also fully aware what could happen if something goes wrong and be prepared for any situation that might happen so it can dealt in a safe and quick manner. The disease should be disposable by professional or a scientist in there located bins which then by transported to a safe area to