DESCRIPTION
Tafluprost is a fluorinated analog of prostaglandin F2α. The chemical name for tafluprost is 1-methylethyl (5Z)-7{(1R, 2R, 3R, 5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-butenyl}-3,5-dihydroxycyclopentyl]-5-heptenoate. The molecular formula of tafluprost is C25H34F2O5 and its molecular weight is 452.53.
Its structural formula is:
Tafluprost is a colorless to light yellow viscous liquid that is practically insoluble in water.
ZIOPTAN® (tafluprost ophthalmic solution) 0.0015% is supplied as a sterile solution of tafluprost with a pH range of 5.5 to 6.7 and an Osmolality range of 260 to 300 mOsmol/kg.
ZIOPTAN® contains Active: tafluprost 0.015 mg/mL, Inactives: glycerol, sodium dihydrogen phosphate dihydrate, disodium edetate,