(2010) performed a study comparing SpayVac (a PZP formulation) to GonaCon-B a gonadotropin-releasing hormone (GnRH) formulation. Both formulations were created as single dose, multi-year antifertility drugs. “SpayVac has been successfully used as a single-dose, multi-year contraceptive in fallow deer, white-tailed deer, grey seals, and captive feral horses” (Gray et al., 2010). GnRH is a key hormone in triggering ovulation, its release triggers the production of several other hormones that set ovulation in motion. Without this hormone, the ovulation process will not be triggered at all. GonaCon-B is a synthetic GnRH product that is too big to be diffused to the anterior pituitary, which is where the other hormones are triggered from, thus the product blocks ovulation. Having a single-dose vaccine that is effective over multiple years would reduce stress on the animals and cut down on the costs of multiple round-ups as well as vaccination via boosters and primers. The main objective in the study by Gray et al. was to determine the effectiveness of the contraceptives for up to three years post-injection
(2010) performed a study comparing SpayVac (a PZP formulation) to GonaCon-B a gonadotropin-releasing hormone (GnRH) formulation. Both formulations were created as single dose, multi-year antifertility drugs. “SpayVac has been successfully used as a single-dose, multi-year contraceptive in fallow deer, white-tailed deer, grey seals, and captive feral horses” (Gray et al., 2010). GnRH is a key hormone in triggering ovulation, its release triggers the production of several other hormones that set ovulation in motion. Without this hormone, the ovulation process will not be triggered at all. GonaCon-B is a synthetic GnRH product that is too big to be diffused to the anterior pituitary, which is where the other hormones are triggered from, thus the product blocks ovulation. Having a single-dose vaccine that is effective over multiple years would reduce stress on the animals and cut down on the costs of multiple round-ups as well as vaccination via boosters and primers. The main objective in the study by Gray et al. was to determine the effectiveness of the contraceptives for up to three years post-injection