John Smith ,62 years old male body weight 160 kg and height 1745cm long term smoker. Today he is consulting his GP with his blood lipid profile which resulted LDL -5.6, HDL -0.4, TG-5.7and total cholesterol -9.4.
Q1. Ideal Total Cholesterol (TC) should be 4 mmol/L or less, LDL-Cholesterol (LDL) should be 3 mmol/L or less and HDL-Cholesterol it should be over 1mmol/L (men) overall Total Cholesterol the lower figure is the better. In Johns result he has Total Cholesterol of 9.40 which is HIGH RISK, LDL of 5.6 is VERY HIGH RISK, HDL of 0.4 is HIGH RISK and Triglyceride level of 5.7 is VERY HIGH RISK of developing a heart disease.
Q2. Chances of developing atherosclerosis in john smith condition increase with the number of risk factors …show more content…
One of the potential reasons for the excess risk of myocardial infarction(MI) or angina is associated with stress. In john’s condition is that stress triggers the sympathetic never systems by releasing hormones such as adrenaline and noradrenaline. Increased sympathetic activity leading to increased blood pressure levels and pulse rates. Also reduced insulin sensitivity or intolerance to glucose and increased blood clotting and blood vessel dysfunction. Reduced blood flow to the heart which resulted with increased respiratory rate. John experience above all response due to his stress since his total cholesterol level revels that he is in high risk in developing atherosclerosis in the arteries. Evidences show that continue to experience stress could leads to heart attack or …show more content…
Glyceryl trinitrate (GTN) is one the most effective drugs for providing rapid symptomatic relief of angina. One of the reason of having chest pain is that the heart is not receiving sufficient amount of oxygen results from atherosclerotic plaques in coronary arteries. Hence, administering glyceryl trinitrate (GTN) to john has allowed potent vasodilation of coronary arteries to increase the blood flow. Their principle benefit follows from a reduction in venous return which reduces the left ventricular work. Aspirin as an antiplatelet drug decrease platelet aggregation and may inhibit further thrombus formation in arterial circulation, including the coronary vessels. Administration of aspirin will prevent John from recurrent