ActA has been shown to have a role in actin rearrangements. Eukaryotic mitochondrial cells transfected with actA display colocalization of ActA with actin indicating ActA has the ability to induce host actin rearrangement (14). Further supporting evidence for the role of actA in L.monocytogenes host intracellular growth is the fact deletion of actA leads to smaller plaque formation on mouse L2 cells (15). Production of ActA and rearranging host actin at a pole allows for L.monocytogenes to be propelled to the cell periphery and facilitate entry into an adjacent …show more content…
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