Lomustine is an alkylating agent and it works by inhibiting DNA replication as the alkyl group binds to the DNA. This then inhibits the growth of the cancer cells. Then, the P-450 system in the liver metabolises this and it is then passed as urine. The recommended dose for lomustine is 130mg per m2. . Lomustine comes in 10mg, 40mg and 100mg strengths.
Lomustine is an alkylating agent and it works by inhibiting DNA replication as the alkyl group binds to the DNA. This then inhibits the growth of the cancer cells. Then, the P-450 system in the liver metabolises this and it is then passed as urine. The recommended dose for lomustine is 130mg per m2. . Lomustine comes in 10mg, 40mg and 100mg strengths.