Weight loss greatly improves the risk of cardiovascular disease associated with PCOS. A sample of 59 obese girls with PCOS aged 12-19 years of age, 26 girls who reduced their weight after 1 year, decreased cFT, insulin concentrations, and homeostatic model assessment, and increased SHBG concentrations. The main challenge is to maintain the weight loss. Pharmacological treatment is another option to reduce PCOS symptoms. Oral contraceptives and insulin sensitizers are effective for adolescents with PCOS in combination of lifestyle intervention or when lifestyle intervention
Weight loss greatly improves the risk of cardiovascular disease associated with PCOS. A sample of 59 obese girls with PCOS aged 12-19 years of age, 26 girls who reduced their weight after 1 year, decreased cFT, insulin concentrations, and homeostatic model assessment, and increased SHBG concentrations. The main challenge is to maintain the weight loss. Pharmacological treatment is another option to reduce PCOS symptoms. Oral contraceptives and insulin sensitizers are effective for adolescents with PCOS in combination of lifestyle intervention or when lifestyle intervention