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33 Cards in this Set
- Front
- Back
1, 3; 2ATP -> 2ADP |
2 steps for priming rxn; rxn |
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4 |
Cleaving step |
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6; 2Pi + 2NAD+ -> 2NADH |
What step includes Oxidation and phosphorylation rxn; rxn |
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1, 3, 7, 10 |
4 Irreversible steps |
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7, 10; 2ADP-> 2ATP |
2 steps for ATP production; rxn |
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1; hexokinase |
Step #; Enzyme in glucose to Glucose 6-Phosphate |
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2; PH I / phosphoGLUCOisomerase |
Step #; Enzyme in G6P to F6P |
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3; PFK-1 |
Step #; Enzyme in F6P to F1,6BP |
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4; Aldolase |
Step #; Enzyme in F1,6BP to G3P and DHAP |
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5; T P I |
Step #; Enzyme in DHAP to G3P |
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6; G3P Dh |
Step #; Enzyme in G3P to 1,3BPG |
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7; PG K |
Step #; Enzyme in 1,3BPG to 3PG |
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8; PG M |
Step #; Enzyme in 3PG to 2PG |
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9; Enolase |
Step #; Enzyme in 2PG to PEP |
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10; PK |
Step #; Enzyme in PEP to Pyruvate |
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9 |
Step in water formation |
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Glucose + 2 (NAD+) + 2ATP yields 2 ADP (1,3) + 2 pyruvate (10) + 2NADH (6) + 4ATP (7,10) + 2H2O (9) |
Overall equation |
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4 ATP (7,10) + 2NADH (2.5 ATP per NADH) = 9ATP |
Total # ATP |
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Prep / investment stage |
-What stage is the Phosphorylation of glucose and conversion to G3P -ATP expense |
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Payoff stage |
Oxidation conversion of G3P to pyruvate and coupled formxn of ATP and NADH |
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G3P |
Cmpd that can only enter payoff stage |
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F1,6BP; 3; PFK-1 |
Committed or key cmpd and step |
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T P I |
What targets DHAP to convert it into G3P |
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Nicotinamide Adenine Dinucleotide |
NAD+ and NADH meaning |
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O: + R: H |
NAD+ or NADH
Oxidized vs Reduced form |
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Intermediate |
Product formed before the actual product |
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2,3-phosphobisglycerate (2,3PBG) |
Intermediate of 3/2 PG Higher affinity to O2 at Hgb |
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Embden-Meyerhoff Pathway |
Glycolysis other name |
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Hexokinase |
Enzyme responsible for glucose Phosphorylation |
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HK II |
Mostly used HK in Glycolysis |
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HK IV / Glucokinase |
HK abundant at hepatocytes in blood |
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Isozymes |
Enzymes that have same func, diff gene composition and struc |
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PFK-1 |
A regulatory enzyme (with the low ATP, it increases to increase glycolysis and pyruvate) |