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9 Cards in this Set
- Front
- Back
What is Gout?
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Inflammatory disease of peripheral joints caused by monosodium urate crystal deposits
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What is the difference between primary and secondary gout?
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Primary gout is d/t inborn error in production or excretion of uric acid
Secondary gout can develop d/t another disease (leukemia, MDS, renal insufficiency) or as a result from certain drugs (salicylates, diuretics, nicotinic acid, alcohol) Secondary can also be induce from a diet high in purines (anchovies, organ meats, liver, spinach, mushrooms, asparagus, oatmeal, cocoa, sweetbreads) |
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Which joint is typically affected with an acute attack of gout?
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MP joint of the big toe (Podagra)
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S&S of an acute gout attack
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Sudden onset of joint inflammation and excruciating pain
Signs include warm, tender, erythematous joint and possibly fever |
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What is Tophi?
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chalky deposits of sodium urate
Tophi seldom become visible until 10 years after the onset of gout |
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What lab value is usually sufficient to establish a dx of gout?
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hyperuricemia
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TX of acute gout
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NSAIDS
Steriods colchinine |
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TX of chronic gout
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urate lowering agents
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When would you start a urate lowering medication after an acute attack and why
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2-4 weeks becaused it may worsen sx
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