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84 Cards in this Set
- Front
- Back
IQ tests |
Wechsler Adult Intelligence Scale (WAIS) - ages 16-75 |
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Objective personality test |
Minnesota Multiphasic Personality Inventory (MMPI-2) |
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DSM-IV Schizophrenia |
A)Two+ for at least 1 month: |
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Schizophrenia subtypes |
1) Paranoid |
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Criteria for Paranoid Type Schizophrenia |
A) Preoccupation with 1+ delusions or frequent AH |
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Criteria for Disorganized Type Schizophrenia |
A) Disorganized speech |
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Criteria for Catatonic Type Schizophrenia |
At least 2 of: |
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Schizophrenia: |
1) 50% |
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Dopamine pathways |
1) Prefrontal cortical - negative sx |
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Neurotransmitter abnormalities in schizophrenia (non-dopamine) |
1) ↑ serotonin |
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Serotonin-antigonizing antipsychotics |
risperidone |
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In schizophrenia: |
Mood sx & acute onset associated w/ better prognosis; negative sx & gradual onset w/ worse. |
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SE of high potency neuroleptics |
High: EPS |
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EPS SE in order of onset |
1) Dystonia |
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Tx of EPS (except TD) |
Anticholinergics (benztropine, amantadine) |
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Tx of TD |
Cholinomimetics |
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Most likely to cause NMS |
High-potency |
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Sx of NMS |
Confusion |
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Which antipsychotic can cause irreversible retinal pigmentation? |
Clozapine |
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Which antipsychotic can cause deposits in lens and cornea? |
Chlorpromazine |
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DSM-IV for schizoaffective d/o |
A) Meet criteria for MDD, manic episode, or mixed episode, during which criteria for schizophrenia also met |
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DSM-IV for Major Depressive Episode |
A) At least five (incl. 1 or 2) for at least 2 weeks: |
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DSM-IV for Manic Episode |
A) At least 1 week of abnormally and persistently elevated, expansive, or irritable mood w/ 3 (4 if irritable): |
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DSM-IV for Mixed Episode |
Criteria met for both manic and major depressive episode, nearly every day for at least 1 week. |
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Hypomanic Episode |
-At least 4 days |
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Sleep problems in MDD |
1) Multiple awakenings |
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Neuroendocrine abnormalities in MDD |
1) High cortisol; failure to suppress in dexamethasone suppression test |
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Monozygotic and dizygotic concordance for MDD |
50% and 10-25% |
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DSM-IV for Bipolar I |
One manic or mixed episode |
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Monozygotic and dizygotic concordance for Bipolar I |
75% and 5-25% |
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DSM-IV for Bipolar II |
One+ MDE and 1+ hypomanic episode |
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DSM-IV for Dysthymic Disorder |
A) Depressed mood most of the time on most days for at least 2 years (1 in chilren) |
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DSM-IV for Cyclothymic Disorder |
A) Numerous periods w/ hypomanic sx and periods w/ depressive sx for at least 2 years |
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Neurotransmitter changes in anxiety |
-↑ NE |
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DSM-IV for panic attacks |
Discrete period of intense fear and discomfort with at least 4 of: |
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DSM-IV for Panic Disorder |
1) Spontaneous recurrent panic attacks |
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Pharm tx for Panic Disorder w/w/o Agoraphobia |
SSRIs first-line |
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DSM-IV for Specific and Social Phobias |
1) Persistent excessive fear |
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Pharm tx for social phobia |
Paroxetine, beta-blockers |
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DSM-IV for OCD |
1) Either obsessions or compulsions |
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Pharm & behavioral tx for OCD |
Pharm: SSRIs, clomipramine |
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DSM-IV PTSD |
-Traumatic, potentially harmful or fatal event; initial reaction intense fear or horror |
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Pharm tx for PTSD |
TCAs (imipramine, doxepin); SSRIs; MAOIs; anticonvulsants (for flashbacks and nightmares) |
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Time lengths in acute stress disorder |
Event occurred <1 month ago |
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DSM-IV for GAD |
1) Excessive anxiety & worry for at least 6 months |
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Pharm tx of GAD |
Buspirone; short course of benzos (clonazepam, diazepam); SSRIs; venlafaxine ER |
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DSM-IV of Adjustment Disorder |
1) Development of emotional or behavioral sx w/in 3 months of a stressful (not life-threatening) event, producing either |
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DSM-IV for personality d/o |
1) Pattern of behavior/inner experience manifested in 2+ of: |
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Cluster A |
-Types: schizoid, schizotypal, paranoid |
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Cluster B |
-Types: antisocial, borderline, histrionic, narcissistic |
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Cluster C |
-Types: avoidant, dependent, obsessive compulsive |
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DSM-IV for substance abuse |
1+ year w/ 1+ of: |
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DSM-IV for substance dependence |
W/in a 12-month period, 3+ of: |
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Legal limit for intoxication in most states |
BAL 80-100 mg/dL |
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Tx of acute EtOH intoxication |
1) ABCs, electrolytes & acid-base |
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Pharm tx for EtOH dependence |
Disulfiram, SSRIs, naltrexone (reduces cravings) |
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Tx of EtOH withdrawal |
1) Tapering benzo |
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Sx of Wernicke's encephalopathy |
1) Ataxia |
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Sx of Korsakoff's syndrome |
1) Impaired recent memory |
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Order of nutrients in Wernicke-Korsakoff |
Thiamine BEFORE glucose |
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Effect of cocaine |
Blocks dopamine reuptake |
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Pharm tx of |
-Intox: benzos, Haldol, sx tx |
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-Classic amphetamines |
-Dextroamphetamine (Dexedrine), methylphenidate (Ritalin), methamphetamine (crystal meth) |
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Effect of |
-Release dopamine from nerve endings |
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How long is urine drug screen + after cocaine use? |
3 days; longer in heavy users |
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How long is urine drug screen + after amphetamine use? |
1-2 days |
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Effects of PCP |
-Antagonizes NMDA glutamate receptors |
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Drug similar to PCP |
Ketamine |
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Pathognomonic sx of PCP intox |
Rotatory nystagmus |
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How long is urine drug screen + after PCP use, and what else is often elevated? |
>1 week; CPK & AST |
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Effect of |
-Increase frequency of Cl channel opening |
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How long is urine drug screen + after sedative-hypnotic use? |
1 week |
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Tx of barbiturate intoxication |
Alkalinize urine w/ sodium bicarb to promote renal excretion |
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Tx for benzo intoxication |
Flumazenil |
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What is the date rape drug? |
GHB (gamma-hydroxybutyrate) |
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What is dextromethorphan? |
An opiate |
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What can meperidine + MAOIs together cause? |
Serotonin syndrome |
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How long is urine test + after opiate use? |
12-36 hours |
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Sx of opiate withdrawal include |
-Dysphoria |
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Which opiate does not cause miosis? |
Meperidine |
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How long is urine test + after MJ use? |
Up to 4 weeks in heavy users |
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How long is serum test + after inhalant use? |
4-10 hours |
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Effect of caffeine |
-Adenosine antagonist → ↑ cAMP |
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Pharm tx for smoking cessation |
Zyban (bupropion), clonidine |