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18 Cards in this Set
- Front
- Back
C reactive protein
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Pentameric protein found in the blood plasma which rises in response to inflammation- binds to phoshocholine expressed on the surface of dead cells
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Low risk c reactive protein
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Less than 1.0 mg/dl
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High risk
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Over 3.0mg/dl
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Types of angina
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Stable, unstable , prinzmental, nocturnal, microvascular
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What is the difference between stable and unstable angina
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Stable- chest discomfort on exercise, lasts for a few minutes, relived with gtn
Unstable- occurs at rest, more severe, crescendo pattern with failure to respond to therapy |
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Acute coronary syndrome- 3 features
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Unstable angina, STEMI, NSTEMI
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ECG changes on angina
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ST depression, t wave inversion, ventricular arrythmia,
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Signs and symptoms of angina
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Chest pain- retrosternal, which radiates down left arm, palpitations, sense of impending doom, nausea and vomitting
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Risk factors
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Smoking, diet, diabetes, high cholestrol, hypertension, age 55 over for men
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Other medical problems with angina
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Hyperthyroidism, anaemia
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Diagnosis
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Resting ECG, cardiac scintography, echocardiogram, cardiac marker level, MRI
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Poor sign on resting ecg
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St segment depression is greater than 1 mm
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Surgical intervention
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Cabg from saphenous vein, angioplasty, internal mammary arterial implantation
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Cardiac markers on angina
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Ck-mb normal , troponin 1 and troponin t is raised
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Treatment pharmo
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Nitroglycerin- converted to NO by aldehyde dehydrogenase and is a potent. Vasodilator
B blocker and calcium channel blocker given Aspirin and statin |
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Other conditions which can cause chest pain
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Pulmonary embolism, aortic
Dissection, pericarditis |
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What is prognostic measure
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Timi
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What is timi
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Ischemic modified albumin, myloperoxidase, gpbb, troponin
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